rs9486916

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele C

OR 0.03

p 1.0e-13

N 607,511

Major Consortium StudyLarge GWAS

multi-ancestry

pulse pressure measurement

Evangelou E et al. “Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.” Nature Genetics 50(10):1412-1425 (2018)

Allele C

OR 0.18

p 2.0e-12

N 757,601

Large GWAS

European

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)

Allele C

OR 0.15

p 3.0e-12

N 1,028,980

Large GWAS

multi-ancestry

Surendran P et al. “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” Nature Genetics 52(12):1314-1332 (2020)

Allele C

OR 0.13

p 5.0e-8

N 810,865

Meta-analysisLarge GWAS

European

systolic blood pressure

Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)

Allele T

OR 0.01

p 4.0e-11

N 1,212,859

Large GWAS

European

Surendran P et al. “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” Nature Genetics 52(12):1314-1332 (2020)

Allele T

OR 0.19

p 1.0e-10

N 1,164,961

Meta-analysisLarge GWAS

European

Allele T

OR 0.21

p 4.0e-11

N 1,028,980

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

rs9486916

GWAS Catalog Trait Associations (3)

body height

pulse pressure measurement

systolic blood pressure

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