rs3743157

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systolic blood pressure

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)

Allele A

OR 0.27

p 9.0e-17

N 1,028,980

Large GWAS

multi-ancestry

Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)

Allele A

OR 0.02

p 3.0e-12

N 1,212,859

Large GWAS

European

Surendran P et al. “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” Nature Genetics 52(12):1314-1332 (2020)

Allele A

OR 0.24

p 4.0e-8

N 810,865

Meta-analysisLarge GWAS

European

Evangelou E et al. “Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.” Nature Genetics 50(10):1412-1425 (2018)

Allele A

OR 0.26

p 1.0e-15

N 757,601

Large GWAS

European

pulse pressure measurement

Allele A

OR 0.16

p 8.0e-12

N 1,028,980

Large GWAS

multi-ancestry

Surendran P et al. “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” Nature Genetics 52(12):1314-1332 (2020)

Allele A

OR 0.13

p 4.0e-8

N 1,164,961

Meta-analysisLarge GWAS

European

diastolic blood pressure

Allele A

OR 0.12

p 8.0e-9

N 1,028,980

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

rs3743157

GWAS Catalog Trait Associations (3)

systolic blood pressure

pulse pressure measurement

diastolic blood pressure

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