CDH2

cadherin 2

Summary

This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]

Known Variants689 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs11564422	18:25,532,080	A/G	—	benign
rs771948589	18:25,532,109	C/G	—	likely benign
rs765791790	18:25,532,125	C/T	—	uncertain significance
rs1909487673	18:25,532,126	A/G	—	likely benign
rs2510768284	18:25,532,131	C/T	—	uncertain significance
rs759051449	18:25,532,141	G/A	—	likely benign
rs1909489908	18:25,532,151	T/C	—	uncertain significance
rs2143852679	18:25,532,159	C/A	—	likely benign
rs201294768	18:25,532,160	C/T	—	uncertain significance
rs1328130862	18:25,532,164	G/A	—	uncertain significance
rs201289431	18:25,532,165	C/G	—	likely benign
rs764584049	18:25,532,167	C/A	—	uncertain significance
rs2510768344	18:25,532,169	C/A	—	uncertain significance
rs200373316	18:25,532,173	C/T	—	uncertain significance
rs201334347	18:25,532,174	G/T	—	uncertain significance
rs1284320594	18:25,532,177	C/T	—	likely benign
rs2510768361	18:25,532,183	A/G	—	likely benign
rs377612781	18:25,532,191	C/T	—	uncertain significance
rs879088485	18:25,532,197	C/T	—	uncertain significance
rs199787442	18:25,532,199	C/G	—	uncertain significance
rs2510768401	18:25,532,203	C/T	—	uncertain significance
rs138164198	18:25,532,208	C/G	—	uncertain significance
rs2510768438	18:25,532,217	T/G	—	uncertain significance
rs1379928255	18:25,532,221	G/C	—	uncertain significance
rs746795245	18:25,532,222	G/A	—	likely benign
rs2510768445	18:25,532,223	G/C	—	uncertain significance
rs1598982439	18:25,532,233	A/G	—	uncertain significance
rs1909497237	18:25,532,235	C/T	—	conflicting classifications of pathogenicity
rs770504867	18:25,532,240	A/C	—	likely benign
rs776296541	18:25,532,241	G/T	—	uncertain significance
rs1909498684	18:25,532,244	G/C	—	uncertain significance
rs2510768479	18:25,532,246	G/A	—	likely benign
rs200803866	18:25,532,247	C/T	—	uncertain significance
rs764766275	18:25,532,251	T/A	—	uncertain significance
rs199653924	18:25,532,276	G/A	—	likely benign
rs1312662447	18:25,532,283	T/C	—	uncertain significance
rs2510768540	18:25,532,285	T/C	—	likely benign
rs2510768544	18:25,532,289	G/A	—	uncertain significance
rs878963425	18:25,532,290	G/A	—	uncertain significance
rs763571811	18:25,532,291	A/C	—	likely benign
rs2289664	18:25,532,304	C/T	—	likely benign
rs2510768572	18:25,532,310	G/A	—	uncertain significance
rs200372513	18:25,532,312	C/A	—	likely benign
rs370333144	18:25,532,313	G/A	—	uncertain significance
rs1293562698	18:25,532,314	C/T	—	uncertain significance
rs2510768621	18:25,532,332	T/G	—	likely benign
rs1427122213	18:25,532,336	A/G	—	likely benign
rs1364193588	18:25,532,338	C/A	—	likely benign
rs1176858882	18:25,532,341	A/G	—	likely benign
rs7229404	18:25,543,140	C/A	—	benign
rs774738448	18:25,543,304	C/T	—	likely benign
rs201711817	18:25,543,305	G/A	—	likely benign
rs199904443	18:25,543,308	T/G	—	likely benign
rs368133718	18:25,543,324	A/G	—	likely benign
rs200254151	18:25,543,325	T/A	—	uncertain significance
rs2011458008	18:25,543,330	G/C	—	uncertain significance
rs147235823	18:25,543,336	C/T	—	likely benign
rs202236593	18:25,543,337	C/T	—	uncertain significance
rs2510776840	18:25,543,338	C/G	—	uncertain significance
rs2011458646	18:25,543,340	A/G	—	uncertain significance
rs201685455	18:25,543,342	G/A	—	likely benign
rs2510776849	18:25,543,346	C/T	—	uncertain significance
rs1302337851	18:25,543,349	G/C	—	uncertain significance
rs2510776861	18:25,543,352	T/C	—	uncertain significance
rs891271607	18:25,543,357	G/A	—	likely benign
rs2143887962	18:25,543,359	C/G	—	uncertain significance
rs199638301	18:25,543,367	C/T	—	uncertain significance
rs2143888013	18:25,543,368	G/A	—	uncertain significance
rs779600795	18:25,543,370	A/G	—	uncertain significance
rs576574544	18:25,543,372	C/T	—	likely benign
rs768097198	18:25,543,373	G/A	—	uncertain significance
rs200230866	18:25,543,382	G/A	—	uncertain significance
rs1476143861	18:25,543,386	C/T	—	uncertain significance
rs1041985	18:25,543,387	G/C	—	likely benign
rs773655778	18:25,543,389	C/T	—	uncertain significance
rs761127424	18:25,543,390	G/T	—	uncertain significance
rs2510776964	18:25,543,396	G/C	—	likely benign
rs2510776966	18:25,543,400	C/A	—	uncertain significance
rs759639016	18:25,543,413	G/A	—	conflicting classifications of pathogenicity
rs2011462344	18:25,543,415	C/T	—	uncertain significance
rs144671067	18:25,543,417	G/T	—	likely benign
rs375175765	18:25,543,432	G/C	—	uncertain significance
rs144790653	18:25,543,447	C/T	—	likely benign
rs1277458415	18:25,543,448	A/G	—	uncertain significance
rs150933422	18:25,543,452	T/G	—	likely benign
rs1037976434	18:25,543,455	C/T	—	uncertain significance
rs2143888523	18:25,543,459	C/A	—	uncertain significance
rs2510777074	18:25,543,463	T/G	—	uncertain significance
rs368266000	18:25,543,477	G/A	—	likely benign
rs3745045	18:25,543,662	T/C	—	benign
rs11083241	18:25,551,961	G/C	—	—
rs8092870	18:25,562,831	C/T	—	benign
rs767390317	18:25,562,892	T/G	—	likely benign
rs750405318	18:25,562,900	C/T	—	likely benign
rs2510790510	18:25,562,914	T/G	—	uncertain significance
rs755903402	18:25,562,923	T/C	—	likely benign
rs2012106745	18:25,562,956	T/C	—	likely benign
rs2510790578	18:25,562,965	A/G	—	likely benign
rs2012106879	18:25,562,971	T/C	—	likely benign
rs1245912880	18:25,562,982	A/G	—	likely benign

Showing 100 of 689 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.