CDH6
cadherin 6
Summary
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs59775462 | 5:31,264,101 | C/G | intron variant | — |
| rs540475400 | 5:31,267,747 | T/A | — | uncertain significance |
| rs147949843 | 5:31,275,611 | T/C | intron variant | — |
| rs4867325 | 5:31,280,457 | T/G | — | — |
| rs777479833 | 5:31,294,088 | G/A | — | uncertain significance |
| rs201394958 | 5:31,294,207 | G/A | — | uncertain significance |
| rs752924110 | 5:31,294,229 | C/T | — | uncertain significance |
| rs575697118 | 5:31,294,255 | G/A | — | uncertain significance |
| rs368076161 | 5:31,302,391 | A/G | — | uncertain significance |
| rs773989887 | 5:31,305,351 | G/A | — | uncertain significance |
| rs1303503328 | 5:31,305,505 | A/C | — | uncertain significance |
| rs764214082 | 5:31,313,501 | A/C | — | uncertain significance |
| rs369010714 | 5:31,316,330 | G/A | — | uncertain significance |
| rs2546663301 | 5:31,317,518 | C/T | — | uncertain significance |
| rs762454450 | 5:31,317,909 | G/A | — | uncertain significance |
| rs1022421171 | 5:31,317,987 | C/G | — | uncertain significance |
| rs184012381 | 5:31,321,488 | C/T | intron variant | — |
| rs756042612 | 5:31,322,943 | C/G | — | uncertain significance |
| rs745499457 | 5:31,323,084 | A/G | — | uncertain significance |
| rs2546667074 | 5:31,323,098 | A/G | — | uncertain significance |
| rs1438205456 | 5:31,323,258 | C/T | — | uncertain significance |
| rs538483207 | 5:31,323,278 | G/T | — | uncertain significance |
| rs1431465518 | 5:31,323,285 | A/G | — | uncertain significance |
| rs2546667401 | 5:31,323,348 | A/G | — | uncertain significance |
| rs780517244 | 5:31,323,366 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.