CDK14
cyclin dependent kinase 14
Summary
Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in G2/M transition of mitotic cell cycle and regulation of canonical Wnt signaling pathway. Located in cytosol; nucleoplasm; and plasma membrane. Part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants32 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1859023 | 7:90,240,585 | A/G | regulatory region variant | — |
| rs10272859 | 7:90,318,474 | G/C | regulatory region variant | — |
| rs6465282 | 7:90,336,270 | C/G | upstream gene variant | — |
| rs528429762 | 7:90,338,895 | G/A | — | uncertain significance |
| rs2535550850 | 7:90,355,897 | T/C | — | uncertain significance |
| rs2535550929 | 7:90,355,929 | G/A | — | uncertain significance |
| rs144891494 | 7:90,355,940 | C/T | — | benign |
| rs1802643390 | 7:90,355,992 | A/G | — | uncertain significance |
| rs746086232 | 7:90,356,061 | A/G | — | uncertain significance |
| rs762863542 | 7:90,356,106 | C/T | — | uncertain significance |
| rs138436598 | 7:90,356,116 | G/A | — | uncertain significance |
| rs767194171 | 7:90,377,012 | T/G | — | uncertain significance |
| rs2535611635 | 7:90,377,059 | T/A | — | uncertain significance |
| rs12666502 | 7:90,427,393 | G/A | intron variant | — |
| rs57870103 | 7:90,483,403 | C/G | intron variant | — |
| rs10487988 | 7:90,486,822 | T/A | intron variant | — |
| rs146138173 | 7:90,492,522 | A/G | — | uncertain significance |
| rs769287160 | 7:90,492,559 | C/T | — | uncertain significance |
| rs376270298 | 7:90,547,013 | C/T | — | uncertain significance |
| rs767090072 | 7:90,585,128 | A/G | — | uncertain significance |
| rs766082964 | 7:90,613,519 | T/C | — | uncertain significance |
| rs751195714 | 7:90,613,520 | G/A | — | uncertain significance |
| rs748125989 | 7:90,708,749 | C/A | — | uncertain significance |
| rs573288226 | 7:90,708,764 | A/G | — | uncertain significance |
| rs942444813 | 7:90,708,782 | C/G | — | uncertain significance |
| rs149042459 | 7:90,741,865 | A/G | — | uncertain significance |
| rs114347546 | 7:90,741,881 | G/A | — | benign |
| rs376448497 | 7:90,741,884 | C/A | — | uncertain significance |
| rs803167 | 7:90,747,315 | A/C | — | — |
| rs145303395 | 7:90,747,439 | C/T | — | uncertain significance |
| rs141334351 | 7:90,747,485 | G/A | — | uncertain significance |
| rs116915466 | 7:90,766,631 | C/G | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.