rs10272859
This is a regulatory region variant variant in the CDK14 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hepatitis B virus infection, hepatocellular carcinoma
Li Y et al. “Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma.” Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 24(4):906-915 (2018)
Allele G
OR 1.28
p 9.0e-10
N 896
Small GWAS
East Asian
About CDK14
Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in G2/M transition of mitotic cell cycle and regulation of canonical Wnt signaling pathway. Located in cytosol; nucleoplasm; and plasma membrane. Part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. [provided by Alliance of Genome Resources, Jul 2025]
View all CDK14 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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