CHMP7
charged multivesicular body protein 7
Summary
Involved in several processes, including midbody abscission; mitotic nuclear division; and vacuolar transport. Located in several cellular components, including bounding membrane of organelle; chromosome; and nucleus. Part of ESCRT III complex and nuclear pore. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142839876 | 8:23,101,025 | C/T | regulatory region variant | — |
| rs7463256 | 8:23,101,620 | T/C | intron variant | — |
| rs7459962 | 8:23,101,743 | C/A | — | — |
| rs760790780 | 8:23,104,273 | C/T | — | uncertain significance |
| rs754334360 | 8:23,104,299 | A/C | — | uncertain significance |
| rs778708248 | 8:23,104,410 | G/T | — | uncertain significance |
| rs1801721241 | 8:23,104,455 | C/T | — | uncertain significance |
| rs2486437652 | 8:23,106,796 | G/T | — | uncertain significance |
| rs572763282 | 8:23,109,904 | A/G | — | — |
| rs554721092 | 8:23,112,861 | C/G | — | uncertain significance |
| rs367547668 | 8:23,112,863 | C/T | — | uncertain significance |
| rs1306311640 | 8:23,114,060 | C/G | — | uncertain significance |
| rs1802133382 | 8:23,114,081 | G/A | — | uncertain significance |
| rs1053189253 | 8:23,114,082 | A/T | — | uncertain significance |
| rs1242418468 | 8:23,115,853 | C/T | — | uncertain significance |
| rs115402987 | 8:23,115,893 | C/T | — | benign |
| rs540027713 | 8:23,115,900 | G/A | — | uncertain significance |
| rs558028323 | 8:23,115,940 | A/G | — | uncertain significance |
| rs1304445583 | 8:23,116,299 | G/A | — | uncertain significance |
| rs35799523 | 8:23,116,325 | C/T | — | benign |
| rs769874873 | 8:23,117,659 | T/A | — | uncertain significance |
| rs747438320 | 8:23,117,680 | A/G | — | uncertain significance |
| rs201195952 | 8:23,117,767 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.