CLEC18A
C-type lectin domain family 18 member A
Summary
This is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C-type lectin domains. These domains bind to carbohydrates in the presence of calcium, and may be involved in cell adhesion, immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]
Known Variants36 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs4985464 | 16:69,978,687 | T/A | — | — |
| rs74249229 | 16:69,979,271 | C/T | downstream gene variant | — |
| rs2650522 | 16:69,980,886 | A/G | — | — |
| rs768301135 | 16:69,985,303 | C/T | — | uncertain significance |
| rs1482258435 | 16:69,985,310 | T/C | — | uncertain significance |
| rs1403458848 | 16:69,985,318 | C/T | — | uncertain significance |
| rs905088634 | 16:69,985,319 | T/A | — | uncertain significance |
| rs201892990 | 16:69,985,340 | C/T | — | uncertain significance |
| rs1486318426 | 16:69,985,350 | G/C | — | uncertain significance |
| rs2548633111 | 16:69,985,355 | G/T | — | uncertain significance |
| rs2058946834 | 16:69,985,366 | C/A | — | uncertain significance |
| rs752771955 | 16:69,985,379 | C/T | — | uncertain significance |
| rs537624010 | 16:69,985,390 | G/A | — | likely benign |
| rs1411603419 | 16:69,985,953 | A/G | — | uncertain significance |
| rs796466650 | 16:69,985,983 | G/A | — | uncertain significance |
| rs1292647909 | 16:69,985,989 | G/A | — | uncertain significance |
| rs1299024495 | 16:69,986,006 | C/T | — | uncertain significance |
| rs1178254692 | 16:69,986,020 | G/A | — | uncertain significance |
| rs2058960337 | 16:69,986,026 | G/T | — | uncertain significance |
| rs71397998 | 16:69,987,751 | G/C | — | — |
| rs766651540 | 16:69,988,328 | C/T | — | uncertain significance |
| rs758953291 | 16:69,988,351 | C/A | — | uncertain significance |
| rs2549095 | 16:69,988,359 | A/T | synonymous variant | — |
| rs1340291007 | 16:69,988,361 | C/G | — | uncertain significance |
| rs533136482 | 16:69,988,418 | G/A | — | likely benign |
| rs763322283 | 16:69,988,436 | G/T | — | uncertain significance |
| rs2548637677 | 16:69,988,439 | A/T | — | uncertain significance |
| rs1369139008 | 16:69,988,445 | C/T | — | uncertain significance |
| rs766149107 | 16:69,988,453 | G/A | — | uncertain significance |
| rs2548637757 | 16:69,988,462 | A/G | — | uncertain significance |
| rs62053354 | 16:69,992,909 | C/T | — | likely benign |
| rs200745923 | 16:69,992,941 | A/G | — | likely benign |
| rs753035905 | 16:69,996,935 | G/C | — | uncertain significance |
| rs572946455 | 16:69,996,947 | G/A | — | uncertain significance |
| rs780705128 | 16:69,996,958 | A/C | — | uncertain significance |
| rs11075748 | 16:69,998,573 | G/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.