CMKLR1
chemerin chemokine-like receptor 1
Summary
Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; positive regulation of macrophage chemotaxis; and regulation of calcium-mediated signaling. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs193215844 | 12:108,682,893 | C/T | 3 prime UTR variant | — |
| rs1384347378 | 12:108,685,679 | G/A | — | uncertain significance |
| rs777870525 | 12:108,685,712 | C/A | — | uncertain significance |
| rs1228583546 | 12:108,685,733 | T/C | — | uncertain significance |
| rs1002902072 | 12:108,685,827 | C/G | — | uncertain significance |
| rs116531815 | 12:108,685,873 | C/A | — | benign |
| rs2540630209 | 12:108,685,911 | G/C | — | uncertain significance |
| rs1326297827 | 12:108,685,916 | G/A | — | uncertain significance |
| rs771537993 | 12:108,685,972 | C/G | — | uncertain significance |
| rs750358962 | 12:108,685,988 | C/A | — | uncertain significance |
| rs760204829 | 12:108,685,994 | C/T | — | uncertain significance |
| rs200130577 | 12:108,686,099 | T/C | — | uncertain significance |
| rs182243804 | 12:108,686,133 | A/T | — | uncertain significance |
| rs374433270 | 12:108,686,135 | G/A | — | uncertain significance |
| rs1891005900 | 12:108,686,145 | C/T | — | uncertain significance |
| rs201961201 | 12:108,686,158 | G/C | — | uncertain significance |
| rs780132798 | 12:108,686,253 | T/C | — | uncertain significance |
| rs1469247569 | 12:108,686,262 | A/G | — | uncertain significance |
| rs777235887 | 12:108,686,268 | T/C | — | likely benign |
| rs771942258 | 12:108,686,362 | G/T | — | uncertain significance |
| rs773573813 | 12:108,686,373 | T/C | — | uncertain significance |
| rs1055891109 | 12:108,686,409 | T/C | — | uncertain significance |
| rs200117272 | 12:108,686,415 | T/A | — | uncertain significance |
| rs768584661 | 12:108,686,517 | T/C | — | uncertain significance |
| rs202104056 | 12:108,686,535 | T/C | — | uncertain significance |
| rs141421422 | 12:108,686,555 | A/C | missense variant | — |
| rs779984645 | 12:108,686,583 | G/A | — | uncertain significance |
| rs2540631758 | 12:108,686,609 | A/G | — | uncertain significance |
| rs761155992 | 12:108,686,610 | C/T | — | uncertain significance |
| rs199548216 | 12:108,686,631 | T/C | — | uncertain significance |
| rs1878022 | 12:108,699,032 | C/T | regulatory region variant | — |
| rs533496184 | 12:108,710,865 | C/A | — | — |
| rs11113818 | 12:108,717,929 | C/A | — | — |
| rs12312487 | 12:108,721,636 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.