CPD
carboxypeptidase D
Summary
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008]
Known Variants80 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs181199485 | 17:28,706,011 | C/A | — | benign |
| rs569399497 | 17:28,706,016 | C/G | — | likely benign |
| rs772650639 | 17:28,706,024 | C/A | — | uncertain significance |
| rs770446630 | 17:28,706,086 | C/T | — | uncertain significance |
| rs1442919170 | 17:28,706,135 | C/T | — | uncertain significance |
| rs2509685898 | 17:28,706,168 | G/C | — | uncertain significance |
| rs1041634728 | 17:28,706,225 | T/G | — | uncertain significance |
| rs1248250862 | 17:28,706,231 | G/T | — | uncertain significance |
| rs1351383869 | 17:28,706,353 | C/G | — | uncertain significance |
| rs978384555 | 17:28,706,368 | C/T | — | uncertain significance |
| rs762738842 | 17:28,706,410 | A/G | — | uncertain significance |
| rs373064492 | 17:28,706,458 | C/T | — | uncertain significance |
| rs779390393 | 17:28,706,468 | C/T | — | uncertain significance |
| rs749312900 | 17:28,706,495 | G/T | — | uncertain significance |
| rs1460795208 | 17:28,706,513 | A/G | — | uncertain significance |
| rs1910987784 | 17:28,706,616 | C/G | — | uncertain significance |
| rs2509686690 | 17:28,706,621 | G/C | — | uncertain significance |
| rs530282755 | 17:28,706,683 | C/T | — | uncertain significance |
| rs2509690119 | 17:28,712,159 | C/G | — | uncertain significance |
| rs193233043 | 17:28,712,161 | A/G | — | uncertain significance |
| rs200206773 | 17:28,712,211 | C/G | — | uncertain significance |
| rs545467829 | 17:28,715,554 | A/G | — | — |
| rs187678828 | 17:28,728,564 | C/T | intron variant | — |
| rs767772875 | 17:28,748,694 | G/A | — | uncertain significance |
| rs761294131 | 17:28,748,716 | C/T | — | uncertain significance |
| rs2509707623 | 17:28,748,769 | C/T | — | uncertain significance |
| rs745350591 | 17:28,748,773 | A/G | — | uncertain significance |
| rs201240868 | 17:28,748,791 | T/G | — | uncertain significance |
| rs748441315 | 17:28,748,821 | G/A | — | uncertain significance |
| rs117331885 | 17:28,749,764 | G/A | — | likely benign |
| rs778524266 | 17:28,749,808 | C/T | — | uncertain significance |
| rs769815696 | 17:28,749,861 | T/C | — | likely benign |
| rs763383514 | 17:28,749,870 | A/G | — | uncertain significance |
| rs61743601 | 17:28,749,880 | A/G | — | benign |
| rs541307210 | 17:28,749,937 | A/G | — | uncertain significance |
| rs531960935 | 17:28,750,544 | A/C | — | uncertain significance |
| rs758310112 | 17:28,754,483 | G/T | — | uncertain significance |
| rs188883639 | 17:28,754,502 | C/T | — | uncertain significance |
| rs759855143 | 17:28,754,572 | T/A | — | uncertain significance |
| rs16965763 | 17:28,758,803 | T/G | — | benign |
| rs756449726 | 17:28,758,898 | A/G | — | uncertain significance |
| rs72809812 | 17:28,760,675 | T/A | regulatory region variant | — |
| rs183787323 | 17:28,765,134 | T/A | intron variant | — |
| rs751150406 | 17:28,766,057 | A/G | — | uncertain significance |
| rs370666752 | 17:28,766,080 | T/C | — | uncertain significance |
| rs2509718770 | 17:28,769,385 | G/T | — | uncertain significance |
| rs2509718809 | 17:28,769,437 | A/G | — | uncertain significance |
| rs758213281 | 17:28,770,866 | G/T | — | uncertain significance |
| rs766518499 | 17:28,772,780 | G/A | — | uncertain significance |
| rs2143475695 | 17:28,772,789 | C/T | — | uncertain significance |
| rs527978533 | 17:28,772,801 | A/G | — | likely benign |
| rs373014036 | 17:28,772,858 | C/T | — | uncertain significance |
| rs1860543 | 17:28,772,861 | C/T | — | benign |
| rs779579879 | 17:28,772,906 | G/C | — | uncertain significance |
| rs192769344 | 17:28,772,926 | C/T | — | uncertain significance |
| rs200096968 | 17:28,772,927 | G/A | — | uncertain significance |
| rs1286804435 | 17:28,776,630 | A/G | — | uncertain significance |
| rs898413996 | 17:28,776,647 | G/A | — | uncertain significance |
| rs760977698 | 17:28,776,659 | C/T | — | uncertain significance |
| rs2509722812 | 17:28,776,668 | G/T | — | uncertain significance |
| rs2509722895 | 17:28,776,752 | C/T | — | uncertain significance |
| rs2011614 | 17:28,781,792 | G/A | intron variant | — |
| rs1444496693 | 17:28,782,390 | T/C | — | uncertain significance |
| rs2509725340 | 17:28,782,434 | T/A | — | uncertain significance |
| rs1406942990 | 17:28,783,515 | G/C | — | uncertain significance |
| rs1182444942 | 17:28,783,525 | G/A | — | uncertain significance |
| rs749273190 | 17:28,788,274 | G/T | — | uncertain significance |
| rs748062282 | 17:28,788,928 | A/G | — | uncertain significance |
| rs2509729460 | 17:28,788,967 | A/G | — | uncertain significance |
| rs1330140261 | 17:28,789,445 | C/T | — | uncertain significance |
| rs568380104 | 17:28,789,446 | G/A | — | uncertain significance |
| rs148102054 | 17:28,791,662 | A/G | — | uncertain significance |
| rs370170270 | 17:28,791,674 | A/G | — | uncertain significance |
| rs755155710 | 17:28,791,681 | A/G | — | uncertain significance |
| rs772586501 | 17:28,791,696 | G/A | — | uncertain significance |
| rs1246758771 | 17:28,791,708 | A/G | — | uncertain significance |
| rs1390503797 | 17:28,791,752 | T/C | — | uncertain significance |
| rs779144998 | 17:28,791,785 | G/A | — | uncertain significance |
| rs184447505 | 17:28,796,255 | T/C | 3 prime UTR variant | — |
| rs181952298 | 17:28,797,197 | A/C | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.