CSNK1A1
casein kinase 1 alpha 1
Summary
Enables protein serine/threonine kinase activity. Involved in several processes, including intermediate filament cytoskeleton organization; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of signal transduction. Located in cytoskeleton and nucleus. Part of beta-catenin destruction complex. Biomarker of Alzheimer's disease and inclusion body myositis. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants3 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2481604661 | 5:148,885,069 | C/T | — | uncertain significance |
| rs752822 | 5:148,889,018 | C/A | — | — |
| rs10058728 | 5:148,904,092 | A/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.