CUL4A

cullin 4A

Summary

CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]

Known Variants29 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs2503851345	13:113,863,988	G/A	—	uncertain significance
rs1163049031	13:113,864,044	G/C	—	uncertain significance
rs953495267	13:113,864,054	G/A	—	uncertain significance
rs866449815	13:113,864,087	G/A	—	uncertain significance
rs1455037982	13:113,864,314	C/G	—	uncertain significance
rs761690889	13:113,864,394	C/G	—	uncertain significance
rs35306827	13:113,869,045	G/A	intron variant	—
rs7985335	13:113,869,244	G/A	—	—
rs35569628	13:113,872,712	T/G	—	—
rs1379704929	13:113,873,353	C/T	—	uncertain significance
rs9549698	13:113,877,701	A/G	intron variant	—
rs7999579	13:113,879,357	T/C	intron variant	—
rs767080315	13:113,883,767	T/A	—	uncertain significance
rs147136485	13:113,887,517	C/T	—	uncertain significance
rs761560555	13:113,887,540	G/A	—	uncertain significance
rs376759372	13:113,887,544	A/G	—	uncertain significance
rs369257799	13:113,887,594	G/A	—	uncertain significance
rs2504084551	13:113,888,245	A/G	—	uncertain significance
rs9549705	13:113,888,425	T/C	intron variant	—
rs56119221	13:113,888,721	C/G	intron variant	—
rs2041496661	13:113,889,452	A/G	—	likely benign
rs766324333	13:113,897,283	C/G	—	uncertain significance
rs375774505	13:113,897,303	A/G	—	uncertain significance
rs1223000474	13:113,900,284	G/T	—	uncertain significance
rs1481932865	13:113,900,300	A/G	—	uncertain significance
rs138665383	13:113,900,349	C/T	—	uncertain significance
rs114695232	13:113,904,818	A/G	intron variant	—
rs779528054	13:113,909,098	T/C	—	uncertain significance
rs182629653	13:113,912,420	C/T	intron variant	—

Gene information from NCBI Gene. Variant classifications from ClinVar.