DLGAP1

DLG associated protein 1

Summary

Predicted to enable molecular adaptor activity. Predicted to be a structural constituent of postsynaptic density. Predicted to be involved in several processes, including aggresome assembly; protein localization to synapse; and regulation of proteasomal protein catabolic process. Predicted to be located in plasma membrane. Predicted to be active in glutamatergic synapse and postsynaptic density, intracellular component. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants84 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs2510074622	18:3,499,196	T/C	—	uncertain significance
rs2510074683	18:3,499,204	G/A	—	likely benign
rs777231021	18:3,502,558	A/G	—	uncertain significance
rs760284072	18:3,502,602	C/T	—	likely benign
rs754917446	18:3,502,618	G/T	—	uncertain significance
rs17724172	18:3,512,216	T/C	regulatory region variant	—
rs12964965	18:3,520,555	T/C	intron variant	—
rs8083633	18:3,522,006	T/C	intron variant	—
rs1208229617	18:3,534,198	C/T	—	uncertain significance
rs73939849	18:3,534,199	G/A	—	benign
rs35822832	18:3,534,224	C/T	—	benign
rs200399766	18:3,534,225	G/A	—	uncertain significance
rs34171157	18:3,534,282	G/A	—	benign
rs758717468	18:3,534,301	G/C	—	uncertain significance
rs35715722	18:3,534,322	G/A	—	benign
rs1027822448	18:3,534,395	G/A	—	uncertain significance
rs988029657	18:3,534,419	C/A	—	uncertain significance
rs140250387	18:3,534,424	A/G	—	likely benign
rs748050566	18:3,534,470	G/A	—	uncertain significance
rs575369187	18:3,534,476	C/T	—	uncertain significance
rs2052212754	18:3,534,495	T/A	—	uncertain significance
rs369615868	18:3,534,519	C/G	—	uncertain significance
rs917274556	18:3,534,524	G/A	—	uncertain significance
rs61732678	18:3,567,568	A/G	—	benign
rs755948170	18:3,581,931	G/A	—	uncertain significance
rs56017170	18:3,581,966	A/G	—	benign
rs911775429	18:3,582,114	C/T	—	uncertain significance
rs4065377	18:3,608,686	T/C	downstream gene variant	—
rs1791373	18:3,616,779	T/G	—	—
rs1110731	18:3,664,989	A/T	regulatory region variant	—
rs1079065	18:3,673,310	C/A	—	—
rs56234957	18:3,729,136	C/T	—	benign
rs3745051	18:3,729,175	T/C	—	benign
rs146904332	18:3,729,178	C/T	—	likely benign
rs201567254	18:3,729,238	C/T	—	likely benign
rs1204292888	18:3,729,240	G/A	—	uncertain significance
rs142690410	18:3,729,292	C/A	—	likely benign
rs148434174	18:3,729,334	G/A	—	likely benign
rs373754921	18:3,729,343	C/T	—	likely benign
rs2512082493	18:3,729,345	C/T	—	uncertain significance
rs149516374	18:3,729,378	G/A	—	likely benign
rs2512265132	18:3,742,355	C/A	—	uncertain significance
rs58247754	18:3,807,662	C/A	—	—
rs11873906	18:3,813,464	G/A	downstream gene variant	—
rs199513653	18:3,814,137	G/A	—	uncertain significance
rs3786431	18:3,814,148	C/G	synonymous variant	benign
rs12607903	18:3,817,134	C/T	regulatory region variant	—
rs141711371	18:3,874,237	C/G	—	benign
rs80137116	18:3,874,604	A/G	—	benign
rs746166320	18:3,874,606	G/A	—	likely benign
rs375283433	18:3,874,707	G/C	—	likely benign
rs146753741	18:3,879,164	G/A	—	uncertain significance
rs61746232	18:3,879,181	C/T	—	benign
rs572366902	18:3,879,209	C/T	—	likely benign
rs145691437	18:3,879,217	G/T	—	benign
rs756463221	18:3,879,288	T/C	—	uncertain significance
rs373210125	18:3,879,336	C/A	—	uncertain significance
rs200889593	18:3,879,413	G/A	—	uncertain significance
rs764609380	18:3,879,441	C/T	—	uncertain significance
rs763053440	18:3,879,502	C/T	—	likely benign
rs767909387	18:3,879,509	C/T	—	uncertain significance
rs770967709	18:3,879,533	C/T	—	uncertain significance
rs201740434	18:3,879,536	T/C	—	uncertain significance
rs761130306	18:3,879,551	G/A	—	uncertain significance
rs141559337	18:3,879,648	G/A	—	likely benign
rs772003344	18:3,879,651	G/C	—	uncertain significance
rs575139844	18:3,879,663	C/T	—	likely benign
rs372254529	18:3,879,716	T/C	—	uncertain significance
rs777255082	18:3,879,724	G/A	—	likely benign
rs76205593	18:3,879,739	C/G	missense variant	—
rs987277339	18:3,879,754	G/C	—	uncertain significance
rs2071106362	18:3,879,900	A/G	—	uncertain significance
rs781481052	18:3,879,921	G/A	—	uncertain significance
rs139426614	18:3,879,984	G/A	—	uncertain significance
rs142650515	18:3,879,987	C/T	—	uncertain significance
rs772737666	18:3,880,012	G/T	—	likely benign
rs1200941976	18:3,880,055	G/A	—	uncertain significance
rs11876749	18:3,942,902	T/A	—	—
rs76325846	18:3,949,621	C/T	intron variant	—
rs73376544	18:3,953,265	C/T	intron variant	—
rs533925746	18:4,105,753	G/A	—	—
rs1402627	18:4,133,739	T/A	—	—
rs534359378	18:4,372,956	G/T	—	—
rs191985391	18:4,434,253	G/T	downstream gene variant	—

Gene information from NCBI Gene. Variant classifications from ClinVar.