DNMBP

dynamin binding protein

Summary

This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Known Variants154 total

rsidPosition (GRCh37)AllelesClassClinVar
rs225628710:101,636,898C/G—benign
rs20182288410:101,636,902G/A—likely benign
rs1119030410:101,636,917T/C—benign
rs74925094310:101,636,961C/G—uncertain significance
rs14624886010:101,636,962G/T—uncertain significance
rs77343745810:101,637,004T/A—uncertain significance
rs249308866010:101,637,054T/C—uncertain significance
rs76002541510:101,639,578T/C—uncertain significance
rs7730708210:101,639,616C/T—benign
rs19996853010:101,639,648C/T—uncertain significance
rs20053062510:101,639,668T/C—likely benign
rs18941283710:101,639,671C/T—uncertain significance
rs14046833810:101,639,681C/T—uncertain significance
rs6175722510:101,639,682G/A—benign
rs11642412010:101,639,728G/A—likely benign
rs203933905610:101,639,758G/A—uncertain significance
rs118567826010:101,639,762C/G—uncertain significance
rs225590110:101,639,796A/G—benign
rs37166179410:101,639,815C/T—uncertain significance
rs1119030510:101,639,877A/C—benign
rs37200312710:101,639,989C/T—uncertain significance
rs14164659610:101,640,015G/A—likely benign
rs77298720410:101,640,056C/T—uncertain significance
rs76631299910:101,640,058G/C—uncertain significance
rs37242702010:101,640,071G/C—uncertain significance
rs37305366110:101,643,851G/A—uncertain significance
rs115701313810:101,643,855C/T—uncertain significance
rs11604688510:101,643,875T/C—uncertain significance
rs144416052010:101,643,884C/T—uncertain significance
rs37759724010:101,643,885G/A—uncertain significance
rs78097793410:101,643,935C/T—uncertain significance
rs74573851210:101,643,936G/A—uncertain significance
rs249310692210:101,643,947G/A—uncertain significance
rs20056912010:101,643,950T/G—uncertain significance
rs123430942810:101,643,951G/A—uncertain significance
rs91323667310:101,645,484G/C—uncertain significance
rs249076310:101,645,498T/C—benign
rs77370032410:101,645,508G/A—uncertain significance
rs76128700010:101,645,528G/C—uncertain significance
rs4129051410:101,645,534G/A—benign
rs77055212410:101,646,058G/A—uncertain significance
rs77725605910:101,646,132G/C—uncertain significance
rs249311369310:101,646,203C/T—uncertain significance
rs54718972810:101,646,214C/T—uncertain significance
rs14067056410:101,646,222C/A—uncertain significance
rs19965425810:101,646,247T/A—uncertain significance
rs76962523410:101,646,278T/C—uncertain significance
rs56949460810:101,646,305G/A—uncertain significance
rs3527767510:101,646,357G/A—benign
rs3588129910:101,646,373C/T—benign
rs77314447110:101,646,374G/A—uncertain significance
rs18481056310:101,648,643C/T—uncertain significance
rs75205375810:101,648,644G/A—uncertain significance
rs139802759410:101,648,655T/C—uncertain significance
rs13853027910:101,648,658A/G—uncertain significance
rs375839410:101,654,696C/T—benign
rs142817410610:101,654,792A/C—uncertain significance
rs374005810:101,655,982G/Aintron variant—
rs249313978610:101,656,048C/T—likely benign
rs76034882710:101,656,118A/G—uncertain significance
rs75955452610:101,656,125T/A—uncertain significance
rs37717637410:101,656,142C/T—uncertain significance
rs98749992410:101,657,873T/C—uncertain significance
rs791932310:101,657,880G/A—benign
rs123424501510:101,657,921C/G—uncertain significance
rs791950710:101,658,021G/C—benign
rs76554606710:101,658,040C/A—uncertain significance
rs11494597010:101,658,504C/T—uncertain significance
rs374005710:101,658,585T/Cintron variant—
rs128146366510:101,659,710G/C—uncertain significance
rs76735665110:101,659,784G/T—uncertain significance
rs1226020310:101,659,795C/T—benign
rs14751079610:101,665,115T/Aintron variant—
rs20123554010:101,667,744G/A—benign
rs1785413510:101,667,792C/T—benign
rs37213534910:101,667,809T/C—uncertain significance
rs1785413410:101,667,814G/A—benign
rs11492764910:101,667,847G/A—benign
rs249317069010:101,668,726G/A—uncertain significance
rs1088342110:101,672,341A/Gintron variant—
rs52995853610:101,673,732T/C—likely benign
rs5584161510:101,681,473G/Aintron variant—
rs707771810:101,689,378C/G—benign
rs14125356410:101,689,389T/C—benign
rs19157312310:101,689,390G/A—benign
rs55270260510:101,689,718T/C—benign
rs7966049710:101,690,096C/T—benign
rs11507342410:101,690,121C/T—benign
rs140988820010:101,690,363C/T—uncertain significance
rs1088342810:101,690,379G/A—benign
rs1119032610:101,690,415A/G—benign
rs708917810:101,693,256T/A——
rs1241526010:101,695,596G/Aintron variant—
rs1088343010:101,704,038T/Cintron variant—
rs55067945510:101,714,988T/C—uncertain significance
rs13787682010:101,715,009T/C—uncertain significance
rs74548640410:101,715,040T/C—uncertain significance
rs249325906310:101,715,042T/C—uncertain significance
rs18376004310:101,715,123C/T—likely benign
rs76932078910:101,715,190T/C—likely benign

Showing 100 of 154 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.