Trait
SNPs associated with Serum Alanine Aminotransferase Amount
1395 genetic variants across 313 genes have been associated with Serum Alanine Aminotransferase Amount in published research. Key genes include A1CF, ABCB1, ABCB11.
Associated variants1,395 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs738409 | PNPLA3 | GWAS association (p=1.0e-45) | Major Consortium Study |
| rs147998249 | GPT | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs112635299 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs738408 | PNPLA3 | GWAS association (p=4.0e-273) | Major Consortium Study |
| rs2862954 | ERLIN1 | GWAS association (p=7.0e-245) | Major Consortium Study |
| rs10733608 | — | GWAS association (p=1.0e-153) | Major Consortium Study |
| rs4835265 | ZNF827 | GWAS association (p=3.0e-124) | Major Consortium Study |
| rs71633359 | — | GWAS association (p=1.0e-96) | Major Consortium Study |
| rs1497406 | EPHA2-AS1 | GWAS association (p=6.0e-91) | Major Consortium Study |
| rs11607757 | — | GWAS association (p=2.0e-83) | Major Consortium Study |
| rs145331563 | GPT | GWAS association (p=4.0e-77) | Major Consortium Study |
| rs17216525 | — | GWAS association (p=2.0e-69) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=7.0e-68) | Major Consortium Study |
| rs4342991 | — | GWAS association (p=2.0e-67) | Major Consortium Study |
| rs132642 | — | GWAS association (p=2.0e-66) | Major Consortium Study |
| rs2642438 | MTARC1 | GWAS association (p=2.0e-64) | Major Consortium Study |
| rs12500824 | — | GWAS association (p=2.0e-62) | Major Consortium Study |
| rs4918722 | GPAM | GWAS association (p=3.0e-62) | Major Consortium Study |
| rs4753124 | — | GWAS association (p=5.0e-62) | Major Consortium Study |
| rs2862926 | — | GWAS association (p=3.0e-61) | Major Consortium Study |
| rs934295 | — | GWAS association (p=7.0e-60) | Major Consortium Study |
| rs9663238 | HKDC1 | GWAS association (p=2.0e-55) | Major Consortium Study |
| rs4940691 | — | GWAS association (p=1.0e-52) | Major Consortium Study |
| rs72613567 | — | GWAS association (p=4.0e-52) | Major Consortium Study |
| rs8178824 | APOH | GWAS association (p=6.0e-52) | Major Consortium Study |
| rs114165349 | — | GWAS association (p=6.0e-47) | Major Consortium Study |
| rs62531503 | — | GWAS association (p=1.0e-45) | Major Consortium Study |
| rs7587 | — | GWAS association (p=2.0e-45) | Major Consortium Study |
| rs5117 | — | GWAS association (p=6.0e-45) | Major Consortium Study |
| rs4782568 | — | GWAS association (p=2.0e-44) | Major Consortium Study |
| rs9625963 | — | GWAS association (p=3.0e-40) | Major Consortium Study |
| rs769449 | APOE | GWAS association (p=9.0e-39) | Major Consortium Study |
| rs132653 | — | GWAS association (p=2.0e-36) | Major Consortium Study |
| rs174537 | MYRF | GWAS association (p=8.0e-36) | Major Consortium Study |
| rs677603 | — | GWAS association (p=2.0e-35) | Major Consortium Study |
| rs1711171 | — | GWAS association (p=3.0e-34) | Major Consortium Study |
| rs11601507 | — | GWAS association (p=1.0e-33) | Major Consortium Study |
| rs13389219 | COBLL1 | GWAS association (p=4.0e-33) | Major Consortium Study |
| rs2304130 | ZNF101 | GWAS association (p=4.0e-33) | Major Consortium Study |
| rs11994207 | ARHGAP39 | GWAS association (p=1.0e-32) | Major Consortium Study |
| rs12968116 | ATP8B1 | GWAS association (p=3.0e-32) | Major Consortium Study |
| rs41276914 | — | GWAS association (p=1.0e-31) | Major Consortium Study |
| rs4420638 | APOC1 | GWAS association (p=2.0e-31) | Major Consortium Study |
| rs445 | CDK6 | GWAS association (p=3.0e-31) | Major Consortium Study |
| rs12002094 | — | GWAS association (p=5.0e-31) | Major Consortium Study |
| rs61804164 | FCGR2B | GWAS association (p=7.0e-31) | Major Consortium Study |
| rs1047891 | CPS1 | GWAS association (p=8.0e-31) | Major Consortium Study |
| rs11735092 | — | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs9668670 | — | GWAS association (p=5.0e-30) | Major Consortium Study |
| rs7422195 | — | GWAS association (p=2.0e-29) | Major Consortium Study |
| rs3812316 | MLXIPL | GWAS association (p=4.0e-29) | Major Consortium Study |
| rs2792759 | GPAM | GWAS association (p=4.0e-29) | Major Consortium Study |
| rs6888304 | — | GWAS association (p=1.0e-28) | Major Consortium Study |
| rs6734238 | — | GWAS association (p=4.0e-28) | Major Consortium Study |
| rs57256140 | — | GWAS association (p=7.0e-28) | Major Consortium Study |
| rs17138478 | — | GWAS association (p=1.0e-27) | Major Consortium Study |
| rs9668186 | — | GWAS association (p=1.0e-27) | Major Consortium Study |
| rs75098626 | — | GWAS association (p=3.0e-27) | Major Consortium Study |
| rs1128249 | — | GWAS association (p=6.0e-27) | Major Consortium Study |
| rs8041057 | — | GWAS association (p=2.0e-26) | Major Consortium Study |
| rs1365298 | — | GWAS association (p=6.0e-26) | Major Consortium Study |
| rs72681869 | SOS2 | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs142042446 | — | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs267733 | ANXA9 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs78569621 | — | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs188273166 | SLC30A10 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs653178 | ATXN2 | GWAS association (p=3.0e-25) | Major Consortium Study |
| rs3129773 | — | GWAS association (p=4.0e-24) | Major Consortium Study |
| rs76015644 | — | GWAS association (p=5.0e-24) | Major Consortium Study |
| rs72832517 | — | GWAS association (p=8.0e-24) | Major Consortium Study |
| rs221057 | — | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs1945784 | HEPHL1 | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs11621792 | — | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs11264341 | TRIM46 | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs73008942 | — | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs1389742 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs34095326 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs11065961 | ATXN2 | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs983309 | — | GWAS association (p=4.0e-22) | Major Consortium Study |
| rs80217587 | — | GWAS association (p=8.0e-22) | Major Consortium Study |
| rs41318029 | ABCC2 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs340029 | RORA | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs739390 | — | GWAS association (p=3.0e-21) | Major Consortium Study |
| rs1658943 | — | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs28421373 | MLXIP | GWAS association (p=9.0e-21) | Major Consortium Study |
| rs58221944 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs13234378 | MLXIPL | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs2943660 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs2787348 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs114020256 | — | GWAS association (p=4.0e-20) | Major Consortium Study |
| rs111576763 | — | GWAS association (p=5.0e-20) | Major Consortium Study |
| rs117527803 | — | GWAS association (p=6.0e-20) | Major Consortium Study |
| rs4808762 | — | GWAS association (p=6.0e-20) | Major Consortium Study |
| rs13106413 | SHROOM3 | GWAS association (p=8.0e-20) | Major Consortium Study |
| rs4244612 | RECQL4 | GWAS association (p=9.0e-20) | Major Consortium Study |
| rs483082 | APOC1 | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs10194882 | — | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs2943652 | — | GWAS association (p=1.0e-19) | Major Consortium Study |
| rs17036101 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs12454712 | BCL2 | GWAS association (p=4.0e-19) | Major Consortium Study |
Showing the top 100 of 1,395 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.