GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
Summary
This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Known Variants54 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1247022675 | 10:113,913,396 | A/C | — | uncertain significance |
| rs1807800 | 10:113,913,552 | A/T | intron variant | — |
| rs1564809366 | 10:113,915,651 | G/A | — | uncertain significance |
| rs2493107816 | 10:113,915,655 | T/C | — | likely benign |
| rs150743685 | 10:113,915,663 | T/C | — | uncertain significance |
| rs2803608 | 10:113,916,302 | T/G | — | — |
| rs2254532 | 10:113,916,835 | A/C | intron variant | — |
| rs2254537 | 10:113,917,085 | T/A | synonymous variant | — |
| rs747200815 | 10:113,918,100 | G/T | — | uncertain significance |
| rs2803609 | 10:113,919,124 | A/G | intron variant | — |
| rs7899096 | 10:113,919,125 | G/T | intron variant | — |
| rs764728397 | 10:113,919,715 | G/A | — | uncertain significance |
| rs767764938 | 10:113,919,722 | G/C | — | uncertain significance |
| rs2493127587 | 10:113,920,388 | T/C | — | uncertain significance |
| rs748557980 | 10:113,920,452 | T/C | — | uncertain significance |
| rs151269022 | 10:113,920,464 | C/G | — | uncertain significance |
| rs202234246 | 10:113,920,572 | G/C | — | uncertain significance |
| rs775676030 | 10:113,920,578 | C/T | — | uncertain significance |
| rs753336467 | 10:113,920,622 | A/G | — | uncertain significance |
| rs2792736 | 10:113,921,159 | T/G | — | — |
| rs760395387 | 10:113,921,429 | C/G | — | uncertain significance |
| rs2803611 | 10:113,922,728 | A/G | intron variant | — |
| rs148432598 | 10:113,923,557 | T/C | — | uncertain significance |
| rs774854082 | 10:113,924,319 | A/G | — | uncertain significance |
| rs73365184 | 10:113,924,331 | G/A | — | benign |
| rs144558318 | 10:113,924,347 | G/T | — | uncertain significance |
| rs34047745 | 10:113,926,184 | A/G | — | benign |
| rs933161984 | 10:113,928,110 | T/C | — | uncertain significance |
| rs746034139 | 10:113,928,198 | C/T | — | uncertain significance |
| rs1210226805 | 10:113,928,201 | A/G | — | uncertain significance |
| rs748375973 | 10:113,928,263 | C/T | — | uncertain significance |
| rs781680553 | 10:113,928,668 | C/G | — | uncertain significance |
| rs2792703 | 10:113,931,690 | C/T | intron variant | — |
| rs2493169783 | 10:113,932,000 | C/T | — | uncertain significance |
| rs2493172782 | 10:113,932,792 | T/A | — | uncertain significance |
| rs5024318 | 10:113,933,009 | T/G | — | — |
| rs141555577 | 10:113,933,560 | C/G | — | uncertain significance |
| rs373088391 | 10:113,933,586 | G/A | — | uncertain significance |
| rs2255141 | 10:113,933,886 | A/G | intron variant | — |
| rs2803619 | 10:113,934,384 | G/C | intron variant | — |
| rs1192281796 | 10:113,935,364 | C/T | — | uncertain significance |
| rs767395257 | 10:113,935,467 | G/A | — | uncertain significance |
| rs2255400 | 10:113,936,244 | A/G | — | — |
| rs2792759 | 10:113,936,855 | C/T | intron variant | — |
| rs1477354296 | 10:113,937,755 | C/T | — | uncertain significance |
| rs2493199313 | 10:113,940,323 | T/C | — | uncertain significance |
| rs2792751 | 10:113,940,329 | T/C | — | benign |
| rs1373191058 | 10:113,941,529 | G/A | — | uncertain significance |
| rs1477396649 | 10:113,941,530 | C/G | — | uncertain significance |
| rs2263608 | 10:113,944,940 | T/A | upstream gene variant | — |
| rs4918722 | 10:113,947,040 | C/A | — | — |
| rs12411732 | 10:113,977,211 | G/A | upstream gene variant | — |
| rs12415159 | 10:113,978,850 | A/T | — | — |
| rs10787431 | 10:113,983,496 | A/G | intergenic variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.