GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

Summary

This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

Known Variants54 total

rsidPosition (GRCh37)AllelesClassClinVar
rs124702267510:113,913,396A/C—uncertain significance
rs180780010:113,913,552A/Tintron variant—
rs156480936610:113,915,651G/A—uncertain significance
rs249310781610:113,915,655T/C—likely benign
rs15074368510:113,915,663T/C—uncertain significance
rs280360810:113,916,302T/G——
rs225453210:113,916,835A/Cintron variant—
rs225453710:113,917,085T/Asynonymous variant—
rs74720081510:113,918,100G/T—uncertain significance
rs280360910:113,919,124A/Gintron variant—
rs789909610:113,919,125G/Tintron variant—
rs76472839710:113,919,715G/A—uncertain significance
rs76776493810:113,919,722G/C—uncertain significance
rs249312758710:113,920,388T/C—uncertain significance
rs74855798010:113,920,452T/C—uncertain significance
rs15126902210:113,920,464C/G—uncertain significance
rs20223424610:113,920,572G/C—uncertain significance
rs77567603010:113,920,578C/T—uncertain significance
rs75333646710:113,920,622A/G—uncertain significance
rs279273610:113,921,159T/G——
rs76039538710:113,921,429C/G—uncertain significance
rs280361110:113,922,728A/Gintron variant—
rs14843259810:113,923,557T/C—uncertain significance
rs77485408210:113,924,319A/G—uncertain significance
rs7336518410:113,924,331G/A—benign
rs14455831810:113,924,347G/T—uncertain significance
rs3404774510:113,926,184A/G—benign
rs93316198410:113,928,110T/C—uncertain significance
rs74603413910:113,928,198C/T—uncertain significance
rs121022680510:113,928,201A/G—uncertain significance
rs74837597310:113,928,263C/T—uncertain significance
rs78168055310:113,928,668C/G—uncertain significance
rs279270310:113,931,690C/Tintron variant—
rs249316978310:113,932,000C/T—uncertain significance
rs249317278210:113,932,792T/A—uncertain significance
rs502431810:113,933,009T/G——
rs14155557710:113,933,560C/G—uncertain significance
rs37308839110:113,933,586G/A—uncertain significance
rs225514110:113,933,886A/Gintron variant—
rs280361910:113,934,384G/Cintron variant—
rs119228179610:113,935,364C/T—uncertain significance
rs76739525710:113,935,467G/A—uncertain significance
rs225540010:113,936,244A/G——
rs279275910:113,936,855C/Tintron variant—
rs147735429610:113,937,755C/T—uncertain significance
rs249319931310:113,940,323T/C—uncertain significance
rs279275110:113,940,329T/C—benign
rs137319105810:113,941,529G/A—uncertain significance
rs147739664910:113,941,530C/G—uncertain significance
rs226360810:113,944,940T/Aupstream gene variant—
rs491872210:113,947,040C/A——
rs1241173210:113,977,211G/Aupstream gene variant—
rs1241515910:113,978,850A/T——
rs1078743110:113,983,496A/Gintergenic variant—

Gene information from NCBI Gene. Variant classifications from ClinVar.