rs112635299

GWAS Catalog Trait Associations (76)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aspartate aminotransferase to alanine aminotransferase ratio

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.39
p 9.9e-324
N 389,192
Major Consortium StudyLarge GWAS
European

serum alanine aminotransferase amount

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.35
p 9.9e-324
N 406,803
Major Consortium StudyLarge GWAS
European

body height

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.38
p 4.0e-298
N 424,305
Major Consortium StudyLarge GWAS
European
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.11
p 2.0e-84
N 525,444
Large GWAS
multi-ancestry

plasma protein metabolism disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.96
p 4.0e-88
N 627,057
Major Consortium StudyLarge GWAS
multi-ancestry

glycoprotein measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.28
p 5.0e-70
N 128,809
Large GWAS
multi-ancestry

amino acid metabolism disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.72
p 3.0e-61
N 620,597
Major Consortium StudyLarge GWAS
multi-ancestry

prostate specific antigen amount

Allele T
OR 0.11
p 2.0e-46
N 392,522
Large GWAS
multi-ancestry
Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.20
p 6.0e-15
N 401,453
Major Consortium StudyLarge GWAS
European
Kachuri L et al. Genetically adjusted PSA levels for prostate cancer screening. Nature Medicine 29(6):1412-1423 (2023)
Allele T
OR 0.11
p 1.0e-15
N 95,768
Large GWAS
multi-ancestry

protein CREG1 measurement

Allele T
OR 0.23
p 1.0e-40
N 47,745
Large GWAS
European

hemoglobin measurement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.12
p 5.0e-37
N 407,887
Major Consortium StudyLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…