rs1711171

GWAS Catalog Trait Associations (10)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cholesteryl esters to total lipids in very small VLDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.03
p 7.0e-39
N 450,015
Large GWAS
multi-ancestry

serum alanine aminotransferase amount

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.03
p 3.0e-34
N 583,801
Major Consortium StudyLarge GWAS
multi-ancestry

free cholesterol to total lipids in IDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.03
p 3.0e-29
N 450,015
Large GWAS
multi-ancestry

isoleucine measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 4.0e-21
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters to total lipids in large HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 4.0e-19
N 450,015
Large GWAS
multi-ancestry

polyunsaturated fatty acids to monounsaturated fatty acids ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 5.0e-18
N 450,015
Large GWAS
multi-ancestry

coronary atherosclerosis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.05
p 1.0e-15
N 602,192
Major Consortium StudyLarge GWAS
multi-ancestry

diet measurement

Allele T
OR 0.01
p 1.0e-8
N 446,443
Major Consortium StudyLarge GWAS
European

serum creatinine amount

Allele T
OR 0.06
p 3.0e-8
N 14,296
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…