Trait
SNPs associated with Coronary Atherosclerosis
82 genetic variants across 37 genes have been associated with Coronary Atherosclerosis in published research. Key genes include ABCG8, ABO, ANGPTL4.
Associated variants82 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10455872 | LPA | GWAS association (p=1.0e-234) | Major Consortium Study |
| rs1537371 | CDKN2B-AS1 | GWAS association (p=3.0e-166) | Major Consortium Study |
| rs9349379 | PHACTR1 | GWAS association (p=2.0e-96) | Major Consortium Study |
| rs12740374 | CELSR2 | GWAS association (p=3.0e-85) | Major Consortium Study |
| rs9515203 | COL4A2 | GWAS association (p=3.0e-54) | Major Consortium Study |
| rs28451064 | — | GWAS association (p=2.0e-51) | Major Consortium Study |
| rs142130958 | — | GWAS association (p=1.0e-44) | Major Consortium Study |
| rs12138316 | — | GWAS association (p=6.0e-44) | Major Consortium Study |
| rs11556924 | ZC3HC1 | GWAS association (p=2.0e-39) | Major Consortium Study |
| rs12190287 | TCF21 | GWAS association (p=2.0e-38) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=5.0e-38) | Major Consortium Study |
| rs1412445 | LIPA | GWAS association (p=9.0e-38) | Major Consortium Study |
| rs10808546 | — | GWAS association (p=2.0e-34) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=3.0e-34) | Major Consortium Study |
| rs494207 | — | GWAS association (p=8.0e-34) | Major Consortium Study |
| rs12151108 | — | GWAS association (p=2.0e-33) | Major Consortium Study |
| rs148513392 | WDR12 | GWAS association (p=8.0e-33) | Major Consortium Study |
| rs10846744 | SCARB1 | GWAS association (p=2.0e-31) | Major Consortium Study |
| rs2019090 | — | GWAS association (p=1.0e-30) | Major Consortium Study |
| rs56375023 | SMAD3 | GWAS association (p=3.0e-29) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=6.0e-29) | Major Consortium Study |
| rs62012629 | — | GWAS association (p=2.0e-28) | Major Consortium Study |
| rs1065853 | — | GWAS association (p=4.0e-28) | Major Consortium Study |
| rs17163360 | MIA3 | GWAS association (p=3.0e-25) | Major Consortium Study |
| rs6227 | FURIN | GWAS association (p=4.0e-25) | Major Consortium Study |
| rs12893887 | HHIPL1 | GWAS association (p=6.0e-25) | Major Consortium Study |
| rs7500448 | — | GWAS association (p=7.0e-25) | Major Consortium Study |
| rs331 | LPL | GWAS association (p=8.0e-25) | Major Consortium Study |
| rs4888372 | — | GWAS association (p=6.0e-23) | Major Consortium Study |
| rs73045269 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs11670056 | — | GWAS association (p=5.0e-22) | Major Consortium Study |
| rs1412444 | LIPA | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs7568458 | GGCX | GWAS association (p=6.0e-21) | Major Consortium Study |
| rs7182103 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs72928605 | CARF | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs2663966 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs606452 | SERPINH1 | GWAS association (p=7.0e-20) | Major Consortium Study |
| rs7766436 | — | GWAS association (p=9.0e-20) | Major Consortium Study |
| rs16986953 | — | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs998584 | POLR1C | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs56062135 | — | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs6807945 | — | GWAS association (p=9.0e-19) | Major Consortium Study |
| rs3184504 | SH2B3 | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs115478735 | ABO | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs116843064 | ANGPTL4 | GWAS association (p=8.0e-18) | Major Consortium Study |
| rs77870048 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs974819 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs2107595 | — | GWAS association (p=4.0e-17) | Major Consortium Study |
| rs56024659 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs7188250 | — | GWAS association (p=9.0e-17) | Major Consortium Study |
| rs12466972 | — | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs11172113 | LRP1 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs3918226 | NOS3 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs72689147 | GUCY1A1 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs3827066 | ZNF335 | GWAS association (p=5.0e-16) | Major Consortium Study |
| rs9337951 | — | GWAS association (p=6.0e-16) | Major Consortium Study |
| rs4299376 | ABCG8 | GWAS association (p=9.0e-16) | Major Consortium Study |
| rs1711171 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs56186267 | PLPP3 | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs28929474 | SERPINA1 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs11191593 | NT5C2 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs17249754 | ATP2B1 | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs8027450 | FURIN | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs13389219 | COBLL1 | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs957293 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs35911833 | HHIPL1 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs526882 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs1790304 | — | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs2943653 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs569014 | — | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs7209460 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs1945392 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs10748858 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs9863 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs11655587 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs6504213 | — | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs4860951 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs61812598 | IL6R | GWAS association (p=5.0e-11) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=8.0e-58) | Major Consortium Study |
| rs147555597 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs2526620 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs682112 | NAV1 | GWAS association (p=1.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.