NAV1
neuron navigator 1
Summary
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Known Variants104 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2068824 | 1:201,594,665 | T/A | — | — |
| rs2464673906 | 1:201,617,845 | A/G | — | uncertain significance |
| rs757489878 | 1:201,617,848 | G/A | — | uncertain significance |
| rs571656889 | 1:201,617,853 | C/A | — | benign |
| rs971315504 | 1:201,617,884 | G/T | — | uncertain significance |
| rs776139888 | 1:201,617,936 | C/G | — | uncertain significance |
| rs377597352 | 1:201,617,997 | C/G | — | uncertain significance |
| rs1669079488 | 1:201,618,016 | A/G | — | likely benign |
| rs144867483 | 1:201,618,040 | G/A | — | benign |
| rs918924263 | 1:201,618,044 | C/T | — | uncertain significance |
| rs753895159 | 1:201,618,158 | G/T | — | uncertain significance |
| rs894248875 | 1:201,618,257 | C/T | — | uncertain significance |
| rs1267119 | 1:201,618,264 | T/C | — | benign |
| rs2464678007 | 1:201,618,452 | C/A | — | uncertain significance |
| rs556637 | 1:201,619,721 | C/G | — | — |
| rs586688 | 1:201,630,955 | G/A | intron variant | — |
| rs545197812 | 1:201,682,770 | G/A | — | — |
| rs369969891 | 1:201,687,567 | G/A | — | uncertain significance |
| rs766836073 | 1:201,687,607 | G/A | — | uncertain significance |
| rs1672232174 | 1:201,687,636 | G/T | — | uncertain significance |
| rs1483137934 | 1:201,687,646 | C/T | — | uncertain significance |
| rs780189061 | 1:201,687,673 | C/T | — | uncertain significance |
| rs746565733 | 1:201,687,702 | G/A | — | uncertain significance |
| rs1672237339 | 1:201,687,739 | G/A | — | uncertain significance |
| rs375709428 | 1:201,687,814 | A/G | — | uncertain significance |
| rs2464980132 | 1:201,687,826 | T/C | — | uncertain significance |
| rs10920250 | 1:201,724,512 | G/A | intron variant | — |
| rs72742024 | 1:201,737,722 | C/T | intron variant | — |
| rs631556 | 1:201,743,185 | G/T | — | — |
| rs516705 | 1:201,743,938 | G/A | regulatory region variant | — |
| rs682112 | 1:201,746,768 | G/C | — | — |
| rs536070 | 1:201,748,800 | T/A | — | — |
| rs61753857 | 1:201,749,691 | C/T | — | likely benign |
| rs760432626 | 1:201,750,140 | C/G | — | uncertain significance |
| rs62623597 | 1:201,750,143 | C/T | — | uncertain significance |
| rs764551413 | 1:201,750,191 | T/C | — | uncertain significance |
| rs143487790 | 1:201,750,276 | G/A | — | uncertain significance |
| rs16849332 | 1:201,750,307 | A/C | — | benign |
| rs146487013 | 1:201,750,347 | C/T | — | uncertain significance |
| rs1471399333 | 1:201,751,345 | G/A | — | uncertain significance |
| rs756027772 | 1:201,751,394 | G/A | — | uncertain significance |
| rs371958868 | 1:201,751,433 | G/A | — | uncertain significance |
| rs1236084772 | 1:201,751,462 | A/G | — | uncertain significance |
| rs200825037 | 1:201,751,518 | C/G | — | benign |
| rs766211014 | 1:201,751,574 | G/A | — | uncertain significance |
| rs759330891 | 1:201,751,633 | C/T | — | uncertain significance |
| rs756860815 | 1:201,751,651 | C/T | — | uncertain significance |
| rs772204331 | 1:201,751,696 | G/A | — | uncertain significance |
| rs1676401962 | 1:201,751,720 | G/A | — | uncertain significance |
| rs764886031 | 1:201,751,813 | C/T | — | uncertain significance |
| rs765917002 | 1:201,751,849 | G/C | — | uncertain significance |
| rs149643745 | 1:201,751,911 | T/C | — | likely benign |
| rs35144347 | 1:201,751,989 | A/C | — | benign |
| rs528789 | 1:201,752,267 | T/A | regulatory region variant | — |
| rs150728227 | 1:201,752,575 | A/G | — | uncertain significance |
| rs770837509 | 1:201,752,626 | C/A | — | uncertain significance |
| rs2465254988 | 1:201,752,644 | T/C | — | uncertain significance |
| rs372376054 | 1:201,752,692 | C/T | — | uncertain significance |
| rs368437984 | 1:201,752,718 | A/G | — | uncertain significance |
| rs142242427 | 1:201,752,781 | C/T | — | uncertain significance |
| rs1676494298 | 1:201,752,789 | G/C | — | uncertain significance |
| rs748683726 | 1:201,752,886 | G/A | — | likely benign |
| rs113832250 | 1:201,752,932 | C/T | — | uncertain significance |
| rs374595704 | 1:201,752,948 | G/C | — | uncertain significance |
| rs762463782 | 1:201,754,446 | G/A | — | uncertain significance |
| rs559557201 | 1:201,755,663 | C/T | — | uncertain significance |
| rs577756420 | 1:201,757,649 | A/T | — | uncertain significance |
| rs748761331 | 1:201,758,895 | C/G | — | uncertain significance |
| rs142843126 | 1:201,759,701 | C/A | — | uncertain significance |
| rs766624611 | 1:201,759,823 | C/T | — | uncertain significance |
| rs146792339 | 1:201,762,928 | G/T | — | benign |
| rs940252055 | 1:201,763,624 | A/G | — | uncertain significance |
| rs2526445800 | 1:201,763,673 | G/A | — | uncertain significance |
| rs3001023 | 1:201,768,789 | A/G | intron variant | — |
| rs12119128 | 1:201,771,326 | G/T | — | — |
| rs369105868 | 1:201,772,736 | G/T | — | uncertain significance |
| rs191072842 | 1:201,772,738 | C/G | — | conflicting classifications of pathogenicity |
| rs1481901169 | 1:201,772,784 | A/G | — | uncertain significance |
| rs775861896 | 1:201,772,817 | C/T | — | uncertain significance |
| rs1329572091 | 1:201,777,145 | C/G | — | uncertain significance |
| rs1280021462 | 1:201,777,265 | C/T | — | likely benign |
| rs114795303 | 1:201,777,553 | G/A | — | benign |
| rs2292822 | 1:201,777,568 | C/T | missense variant | — |
| rs753008409 | 1:201,777,623 | C/T | — | uncertain significance |
| rs75689268 | 1:201,777,690 | C/T | — | benign |
| rs1678467875 | 1:201,777,722 | C/A | — | uncertain significance |
| rs775045348 | 1:201,777,943 | G/A | — | uncertain significance |
| rs141703547 | 1:201,777,945 | C/T | — | uncertain significance |
| rs146240659 | 1:201,777,978 | G/A | — | likely benign |
| rs779906871 | 1:201,777,996 | A/G | — | uncertain significance |
| rs747956225 | 1:201,778,601 | G/C | — | uncertain significance |
| rs145643487 | 1:201,779,190 | T/G | — | benign |
| rs755581838 | 1:201,779,219 | C/T | — | uncertain significance |
| rs16849379 | 1:201,779,668 | G/A | — | benign |
| rs150946974 | 1:201,779,677 | C/T | — | benign |
| rs2526576851 | 1:201,781,722 | G/A | — | likely benign |
| rs138579441 | 1:201,786,220 | A/G | — | uncertain significance |
| rs749859308 | 1:201,786,390 | A/G | — | uncertain significance |
| rs116246396 | 1:201,786,413 | G/C | — | benign |
| rs2494112 | 1:201,787,833 | G/A | intron variant | — |
Showing 100 of 104 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.