rs72928605

This is a intron variant variant in the CARF gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

coronary atherosclerosis

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele A

OR 0.08

p 1.0e-20

N 602,192

Major Consortium StudyLarge GWAS

multi-ancestry

drug use measurement, coronary artery disease

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele A

OR 0.09

p 1.0e-14

N 404,034

Major Consortium StudyLarge GWAS

multi-ancestry

About CARF

Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in cellular response to calcium ion. Predicted to be located in granular component. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all CARF variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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