ZNF827
zinc finger protein 827
Summary
Enables NuRD complex binding activity. Involved in several processes, including establishment of protein localization to telomere; negative regulation of shelterin complex assembly; and telomere maintenance. Located in chromatin and chromosome, telomeric region. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants80 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs148875276 | 4:146,686,150 | C/T | — | uncertain significance |
| rs1230534189 | 4:146,686,312 | C/T | — | uncertain significance |
| rs781521090 | 4:146,686,744 | G/A | — | uncertain significance |
| rs2546517968 | 4:146,686,861 | T/C | — | uncertain significance |
| rs113470073 | 4:146,686,863 | G/A | — | uncertain significance |
| rs150430236 | 4:146,695,673 | C/T | — | uncertain significance |
| rs1425617575 | 4:146,695,735 | G/A | — | uncertain significance |
| rs35479210 | 4:146,695,800 | G/A | — | benign |
| rs147131944 | 4:146,696,987 | C/T | — | uncertain significance |
| rs758360777 | 4:146,697,100 | T/C | — | uncertain significance |
| rs746428731 | 4:146,700,564 | C/T | — | uncertain significance |
| rs747021254 | 4:146,700,586 | C/T | — | uncertain significance |
| rs7688389 | 4:146,710,005 | C/G | — | — |
| rs766723712 | 4:146,744,606 | T/A | — | uncertain significance |
| rs947629040 | 4:146,744,613 | G/C | — | uncertain significance |
| rs74731224 | 4:146,744,641 | T/A | — | benign |
| rs775397521 | 4:146,744,648 | T/G | — | uncertain significance |
| rs13149290 | 4:146,750,966 | C/T | regulatory region variant | — |
| rs4835260 | 4:146,765,560 | G/T | — | — |
| rs1027841 | 4:146,769,074 | G/A | intron variant | — |
| rs1579367176 | 4:146,770,497 | G/T | — | uncertain significance |
| rs778190302 | 4:146,770,561 | G/A | — | uncertain significance |
| rs143277821 | 4:146,770,563 | A/G | — | uncertain significance |
| rs775752510 | 4:146,770,590 | C/T | — | uncertain significance |
| rs757994158 | 4:146,770,657 | C/T | — | uncertain significance |
| rs7669911 | 4:146,789,485 | C/T | intron variant | — |
| rs760851909 | 4:146,791,508 | A/G | — | likely benign |
| rs767106459 | 4:146,791,543 | C/G | — | uncertain significance |
| rs143420805 | 4:146,791,556 | T/C | — | likely benign |
| rs755320765 | 4:146,791,606 | T/A | — | uncertain significance |
| rs4293803 | 4:146,793,627 | G/C | intron variant | — |
| rs4547811 | 4:146,794,621 | T/A | — | — |
| rs28590383 | 4:146,803,248 | T/C | regulatory region variant | — |
| rs368474421 | 4:146,806,944 | C/A | — | uncertain significance |
| rs199767989 | 4:146,806,947 | G/A | — | uncertain significance |
| rs369098617 | 4:146,807,025 | A/G | — | uncertain significance |
| rs374572235 | 4:146,807,028 | C/G | — | uncertain significance |
| rs141750019 | 4:146,807,082 | C/T | — | uncertain significance |
| rs2546865532 | 4:146,807,096 | C/G | — | uncertain significance |
| rs36007872 | 4:146,809,578 | G/T | regulatory region variant | — |
| rs10006310 | 4:146,809,998 | T/G | intron variant | — |
| rs35749556 | 4:146,810,028 | C/A | intron variant | — |
| rs67613802 | 4:146,812,843 | C/T | — | — |
| rs536406751 | 4:146,813,504 | T/C | — | uncertain significance |
| rs753753436 | 4:146,813,544 | G/C | — | uncertain significance |
| rs756798998 | 4:146,813,550 | C/T | — | uncertain significance |
| rs7678352 | 4:146,814,317 | C/T | intron variant | — |
| rs4835265 | 4:146,821,410 | C/A | intron variant | — |
| rs368218251 | 4:146,823,350 | G/A | — | uncertain significance |
| rs2546898902 | 4:146,823,378 | A/T | — | uncertain significance |
| rs759748128 | 4:146,823,413 | G/A | — | uncertain significance |
| rs1358724274 | 4:146,823,419 | G/A | — | uncertain significance |
| rs756668430 | 4:146,823,465 | G/A | — | uncertain significance |
| rs1751502887 | 4:146,823,603 | C/A | — | uncertain significance |
| rs765679883 | 4:146,823,705 | G/A | — | likely benign |
| rs200202481 | 4:146,823,734 | T/C | — | uncertain significance |
| rs779034544 | 4:146,823,744 | G/C | — | uncertain significance |
| rs376372736 | 4:146,823,797 | C/G | — | uncertain significance |
| rs202025645 | 4:146,823,818 | G/C | — | uncertain significance |
| rs2546900674 | 4:146,823,821 | A/T | — | uncertain significance |
| rs1211914623 | 4:146,823,825 | A/G | — | uncertain significance |
| rs746475491 | 4:146,823,848 | C/T | — | uncertain significance |
| rs200909694 | 4:146,823,888 | C/T | — | uncertain significance |
| rs575173942 | 4:146,823,925 | G/A | — | likely benign |
| rs750203022 | 4:146,823,938 | G/A | — | uncertain significance |
| rs142710372 | 4:146,823,939 | G/A | — | uncertain significance |
| rs575186320 | 4:146,823,969 | C/T | — | uncertain significance |
| rs149785116 | 4:146,824,064 | T/C | — | uncertain significance |
| rs371065551 | 4:146,824,115 | T/C | — | uncertain significance |
| rs200049079 | 4:146,824,179 | T/C | — | uncertain significance |
| rs201229699 | 4:146,824,205 | G/A | — | uncertain significance |
| rs2546902108 | 4:146,824,233 | T/A | — | uncertain significance |
| rs771868329 | 4:146,824,236 | G/A | — | uncertain significance |
| rs149206051 | 4:146,824,292 | G/A | — | uncertain significance |
| rs771099583 | 4:146,824,297 | C/G | — | uncertain significance |
| rs768466793 | 4:146,824,310 | C/T | — | uncertain significance |
| rs753161817 | 4:146,824,358 | C/T | — | uncertain significance |
| rs576668364 | 4:146,840,491 | C/T | — | — |
| rs2135963 | 4:146,844,104 | C/G | intron variant | — |
| rs2048161 | 4:146,853,165 | A/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.