FEZF1
FEZ family zinc finger 1
Summary
This gene encodes a transcriptional repressor that belongs to the zinc finger double domain protein family. The encoded protein is thought to play a role in the embryonic migration of gonadotropin-releasing hormone neurons into the brain. Mutations in this gene are associated with hypogonadotropic hypogonadism-22 with anosmia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Known Variants73 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs754661273 | 7:121,942,057 | G/A | — | likely benign |
| rs778923284 | 7:121,942,062 | C/T | — | uncertain significance |
| rs373295088 | 7:121,942,064 | T/C | — | uncertain significance |
| rs577039958 | 7:121,942,082 | A/C | — | uncertain significance |
| rs1465527727 | 7:121,942,086 | G/T | — | uncertain significance |
| rs1243641294 | 7:121,942,106 | G/T | — | uncertain significance |
| rs112066691 | 7:121,942,129 | C/T | — | benign |
| rs766021955 | 7:121,942,130 | G/A | — | uncertain significance |
| rs561681709 | 7:121,942,136 | T/G | — | likely benign |
| rs775695735 | 7:121,942,156 | C/T | — | likely benign |
| rs2485174122 | 7:121,942,161 | C/G | — | uncertain significance |
| rs2031069981 | 7:121,942,293 | C/T | — | uncertain significance |
| rs142377395 | 7:121,942,315 | G/A | — | likely benign |
| rs77532529 | 7:121,942,526 | A/G | — | benign |
| rs11978249 | 7:121,942,621 | G/A | — | benign |
| rs6968240 | 7:121,942,674 | C/A | — | benign |
| rs368199722 | 7:121,942,838 | T/C | — | benign |
| rs6968786 | 7:121,942,847 | C/G | — | benign |
| rs117528546 | 7:121,942,849 | G/A | — | benign |
| rs148805926 | 7:121,942,902 | G/C | — | likely benign |
| rs1373882145 | 7:121,942,907 | C/T | — | uncertain significance |
| rs78309987 | 7:121,942,920 | A/G | — | likely benign |
| rs369157481 | 7:121,942,995 | A/C | — | likely benign |
| rs1250293488 | 7:121,943,214 | G/A | — | likely benign |
| rs188460649 | 7:121,943,382 | C/T | — | benign |
| rs148147097 | 7:121,943,433 | G/C | — | likely benign |
| rs190075869 | 7:121,943,566 | A/G | — | likely benign |
| rs182132856 | 7:121,943,570 | A/G | — | benign |
| rs11974164 | 7:121,943,590 | A/G | — | benign |
| rs139019500 | 7:121,943,632 | G/A | — | likely benign |
| rs111662975 | 7:121,943,642 | A/G | — | benign |
| rs62476008 | 7:121,943,681 | T/A | — | likely benign |
| rs2485179005 | 7:121,943,705 | C/T | — | uncertain significance |
| rs369460018 | 7:121,943,712 | G/A | — | likely benign |
| rs2485179036 | 7:121,943,713 | A/G | — | uncertain significance |
| rs527670913 | 7:121,943,740 | C/G | — | uncertain significance |
| rs756663519 | 7:121,943,757 | G/C | — | likely benign |
| rs2485179361 | 7:121,943,781 | C/A | — | likely benign |
| rs749403794 | 7:121,943,815 | A/C | — | uncertain significance |
| rs757983995 | 7:121,943,877 | C/T | — | likely benign |
| rs938528614 | 7:121,943,902 | T/C | — | uncertain significance |
| rs370467502 | 7:121,943,939 | A/G | — | likely benign |
| rs570196942 | 7:121,943,969 | C/G | — | likely benign |
| rs2485180371 | 7:121,943,988 | G/A | — | likely benign |
| rs755972168 | 7:121,943,998 | C/G | — | uncertain significance |
| rs747228982 | 7:121,944,029 | G/A | — | uncertain significance |
| rs771460949 | 7:121,944,043 | T/C | — | uncertain significance |
| rs866141957 | 7:121,944,052 | C/T | — | uncertain significance |
| rs374950795 | 7:121,944,054 | C/T | — | likely benign |
| rs778010186 | 7:121,944,087 | C/T | — | likely benign |
| rs2485180898 | 7:121,944,098 | C/T | — | uncertain significance |
| rs537105864 | 7:121,944,122 | C/A | — | uncertain significance |
| rs1182014767 | 7:121,944,187 | G/A | — | uncertain significance |
| rs151311760 | 7:121,944,207 | C/G | — | likely benign |
| rs1218083905 | 7:121,944,226 | C/T | — | uncertain significance |
| rs893917390 | 7:121,944,229 | G/A | — | uncertain significance |
| rs914972337 | 7:121,944,238 | C/T | — | uncertain significance |
| rs145467198 | 7:121,944,239 | T/C | — | likely benign |
| rs1044842458 | 7:121,944,240 | C/T | — | likely benign |
| rs2031188275 | 7:121,944,242 | T/A | — | uncertain significance |
| rs142331989 | 7:121,944,279 | G/A | — | likely benign |
| rs758386407 | 7:121,944,295 | T/G | — | uncertain significance |
| rs1221347151 | 7:121,944,304 | T/C | — | uncertain significance |
| rs757305012 | 7:121,944,308 | T/C | — | uncertain significance |
| rs781329012 | 7:121,944,312 | T/C | — | likely benign |
| rs1328821442 | 7:121,944,326 | A/C | — | likely benign |
| rs776213039 | 7:121,944,369 | T/A | — | likely benign |
| rs2485182647 | 7:121,944,377 | G/A | — | uncertain significance |
| rs1465965223 | 7:121,944,418 | G/T | — | uncertain significance |
| rs2031200782 | 7:121,944,427 | A/T | — | uncertain significance |
| rs750664723 | 7:121,944,437 | G/A | — | uncertain significance |
| rs11761299 | 7:121,944,527 | T/C | — | benign |
| rs553825137 | 7:121,952,012 | C/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.