FILIP1

filamin A interacting protein 1

Summary

This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016]

Known Variants70 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1459010236:76,018,420C/G—uncertain significance
rs1416762506:76,018,565T/G—uncertain significance
rs7780342266:76,018,609C/G—uncertain significance
rs47081786:76,021,338A/T——
rs7631266336:76,022,150G/A—pathogenic
rs352271906:76,022,171G/A—likely benign
rs7548210146:76,022,189G/C—uncertain significance
rs17732344406:76,022,211T/C—uncertain significance
rs3748879166:76,022,232C/G—benign
rs5310184236:76,022,447C/T—uncertain significance
rs2012832166:76,022,448G/A—uncertain significance
rs1487563136:76,022,454T/C—uncertain significance
rs14364921026:76,022,519A/C—uncertain significance
rs348071696:76,022,541G/A—benign
rs3726712376:76,022,565C/T—uncertain significance
rs7658507636:76,022,614C/T—uncertain significance
rs14277682906:76,022,665C/T—uncertain significance
rs12117139226:76,022,671G/T—uncertain significance
rs7751416166:76,022,883G/A—pathogenic
rs1410908956:76,023,032C/T—uncertain significance
rs7559254796:76,023,075G/A—uncertain significance
rs5780802756:76,023,114C/T—likely benign
rs7734106116:76,023,134A/G—uncertain significance
rs785666206:76,023,146G/A—uncertain significance
rs5429388446:76,023,207G/A—uncertain significance
rs354499486:76,023,414A/G—benign
rs11652575536:76,023,467A/G—uncertain significance
rs14358911856:76,023,499C/A—uncertain significance
rs7785199396:76,023,602A/G—uncertain significance
rs10571752206:76,023,758T/C—uncertain significance
rs14493271786:76,023,865C/T—uncertain significance
rs25338927036:76,023,905A/G—uncertain significance
rs9725882806:76,024,060A/C—uncertain significance
rs354648306:76,024,065T/C—likely benign
rs25338955996:76,024,235A/G—uncertain significance
rs10051531426:76,024,282T/G—uncertain significance
rs2021780496:76,024,391C/T—uncertain significance
rs1417664196:76,024,392G/A—uncertain significance
rs617361886:76,024,419T/C—benign
rs7743861976:76,024,460C/T—uncertain significance
rs7676245966:76,024,466T/C—uncertain significance
rs3710508806:76,024,625G/A—uncertain significance
rs1870017236:76,024,638C/T—uncertain significance
rs341481866:76,024,711T/C—benign
rs7661579876:76,024,803T/G—uncertain significance
rs7699425346:76,024,821G/A—uncertain significance
rs9523777126:76,024,859G/A—uncertain significance
rs7806053456:76,024,901T/G—uncertain significance
rs715614246:76,024,910T/G—uncertain significance
rs1497622286:76,063,292C/T—uncertain significance
rs1458768006:76,063,301T/G—uncertain significance
rs7574364126:76,063,351C/T—uncertain significance
rs1424908726:76,063,368G/A—likely benign
rs1435028756:76,063,393C/T—uncertain significance
rs25340423456:76,063,421C/A—pathogenic
rs3772504976:76,072,470G/A—uncertain significance
rs7505251426:76,072,494A/G—uncertain significance
rs3720004266:76,072,537G/A—uncertain significance
rs7794370846:76,072,612T/C—uncertain significance
rs7652640646:76,072,672T/Ccoding sequence variant—
rs7793506916:76,124,520G/A—pathogenic
rs25342497126:76,124,525A/T—uncertain significance
rs9625660476:76,124,532C/G—uncertain significance
rs1386681336:76,124,558C/T—uncertain significance
rs1122400666:76,124,616C/T—likely benign
rs7638011676:76,124,658C/T—uncertain significance
rs1501446986:76,172,518C/Tupstream gene variant—
rs109432496:76,199,219C/Tregulatory region variant—
rs174966646:76,199,697C/Tintron variant—
rs93432926:76,202,656A/Gregulatory region variant—

Gene information from NCBI Gene. Variant classifications from ClinVar.