FOXA3
forkhead box A3
Summary
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs547423844 | 19:46,367,706 | G/C | — | likely benign |
| rs202075556 | 19:46,373,049 | A/T | — | — |
| rs2513811547 | 19:46,375,360 | A/C | — | uncertain significance |
| rs1238118796 | 19:46,375,372 | C/A | — | uncertain significance |
| rs543169864 | 19:46,375,516 | G/A | — | uncertain significance |
| rs752761784 | 19:46,375,522 | A/G | — | likely benign |
| rs150013684 | 19:46,375,529 | G/A | — | uncertain significance |
| rs1314889853 | 19:46,375,550 | G/C | — | uncertain significance |
| rs144459600 | 19:46,375,608 | T/C | — | benign |
| rs1369578379 | 19:46,375,641 | C/G | — | uncertain significance |
| rs772555492 | 19:46,375,741 | C/A | — | uncertain significance |
| rs16980091 | 19:46,375,779 | T/C | — | benign |
| rs752376903 | 19:46,375,802 | G/C | — | uncertain significance |
| rs200743469 | 19:46,375,974 | T/C | — | likely benign |
| rs749657388 | 19:46,375,979 | C/T | — | uncertain significance |
| rs773364143 | 19:46,375,988 | C/G | — | uncertain significance |
| rs750062748 | 19:46,376,012 | C/T | — | uncertain significance |
| rs1196201504 | 19:46,376,087 | C/T | — | uncertain significance |
| rs541734780 | 19:46,376,137 | C/G | — | likely benign |
| rs138611202 | 19:46,376,149 | G/A | — | uncertain significance |
| rs3810327 | 19:46,376,217 | C/A | — | benign |
| rs146135785 | 19:46,376,226 | C/T | — | likely benign |
| rs377404065 | 19:46,376,245 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.