G3BP2
G3BP stress granule assembly factor 2
Summary
Enables molecular condensate scaffold activity. Involved in positive regulation of stress granule assembly; protein homooligomerization; and stress granule assembly. Located in cytoplasmic stress granule and cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs78728557 | 4:76,567,944 | T/C | downstream gene variant | — |
| rs1235059529 | 4:76,570,640 | C/T | — | uncertain significance |
| rs529840020 | 4:76,570,647 | T/A | — | uncertain significance |
| rs2476697778 | 4:76,570,882 | A/C | — | uncertain significance |
| rs2476758697 | 4:76,573,913 | C/T | — | uncertain significance |
| rs139334533 | 4:76,573,917 | G/A | — | likely benign |
| rs150020326 | 4:76,579,196 | G/A | — | uncertain significance |
| rs748840062 | 4:76,580,321 | C/G | — | uncertain significance |
| rs146775757 | 4:76,580,368 | T/C | — | uncertain significance |
| rs777878492 | 4:76,580,980 | T/A | — | uncertain significance |
| rs549953316 | 4:76,625,280 | C/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.