GIMAP6
GTPase, IMAP family member 6
Summary
This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. [provided by RefSeq, Sep 2011]
Known Variants33 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2485740458 | 7:150,324,811 | A/G | — | uncertain significance |
| rs3735084 | 7:150,324,825 | C/T | — | benign |
| rs1490398919 | 7:150,324,832 | C/T | — | uncertain significance |
| rs113226331 | 7:150,324,918 | G/T | — | benign |
| rs201383570 | 7:150,324,956 | G/A | — | uncertain significance |
| rs11977216 | 7:150,324,976 | T/C | — | benign |
| rs779061760 | 7:150,325,052 | G/T | — | uncertain significance |
| rs1796323881 | 7:150,325,060 | T/C | — | uncertain significance |
| rs752336307 | 7:150,325,094 | C/T | — | likely benign |
| rs200301890 | 7:150,325,102 | C/T | — | uncertain significance |
| rs372190402 | 7:150,325,143 | G/C | — | uncertain significance |
| rs747155481 | 7:150,325,144 | T/C | — | uncertain significance |
| rs13234724 | 7:150,325,175 | C/T | — | benign |
| rs376869789 | 7:150,325,195 | C/T | — | uncertain significance |
| rs1044027422 | 7:150,325,196 | G/A | — | uncertain significance |
| rs1369736162 | 7:150,325,270 | T/C | — | uncertain significance |
| rs2485742955 | 7:150,325,276 | T/A | — | uncertain significance |
| rs757367483 | 7:150,325,297 | G/A | — | uncertain significance |
| rs1370590200 | 7:150,325,313 | C/T | — | uncertain significance |
| rs747812177 | 7:150,325,318 | G/A | — | uncertain significance |
| rs201051041 | 7:150,325,337 | C/T | — | likely benign |
| rs375860624 | 7:150,325,355 | C/T | — | uncertain significance |
| rs114540180 | 7:150,325,378 | T/C | — | benign |
| rs746468152 | 7:150,325,384 | G/T | — | uncertain significance |
| rs767832540 | 7:150,325,429 | C/T | — | likely pathogenic |
| rs376322381 | 7:150,325,435 | C/G | — | uncertain significance |
| rs753036235 | 7:150,325,444 | C/T | — | uncertain significance |
| rs375893282 | 7:150,325,487 | C/T | — | uncertain significance |
| rs17173519 | 7:150,325,493 | C/T | — | benign |
| rs150982153 | 7:150,325,529 | T/C | — | uncertain significance |
| rs1277737851 | 7:150,325,573 | G/T | — | uncertain significance |
| rs747335625 | 7:150,327,180 | C/A | — | uncertain significance |
| rs62491812 | 7:150,327,424 | C/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.