GPC6

glypican 6

Summary

The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1. [provided by RefSeq, Nov 2016]

Known Variants311 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1770247113:93,877,117A/Gregulatory region variant—
rs798589113:93,879,031A/Gregulatory region variantbenign
rs31952213:93,879,087A/G—benign
rs96046030613:93,879,232C/G—uncertain significance
rs88605034813:93,879,268C/T—uncertain significance
rs1764596913:93,879,390A/C—benign
rs18414288813:93,879,403T/A—uncertain significance
rs119561864213:93,879,462G/A—uncertain significance
rs18845023513:93,879,573C/T—benign
rs55016518713:93,879,577G/T—uncertain significance
rs187582538313:93,879,597G/A—uncertain significance
rs53590492813:93,879,610G/A—uncertain significance
rs53396599513:93,879,641C/T—uncertain significance
rs57413143413:93,879,687G/T—uncertain significance
rs20092524913:93,879,719T/A—likely benign
rs146861838813:93,879,729C/A—uncertain significance
rs119298185413:93,879,733G/C—likely benign
rs77942922513:93,879,752C/T—likely benign
rs74846489313:93,879,758C/A—uncertain significance
rs136967145613:93,879,769C/T—likely benign
rs15002323313:93,879,773G/C—uncertain significance
rs14663872113:93,879,787G/A—likely benign
rs76275304813:93,879,792G/C—uncertain significance
rs53141290213:93,879,802A/G—likely benign
rs14017725713:93,879,805G/C—conflicting classifications of pathogenicity
rs131804049113:93,879,822G/C—uncertain significance
rs78159963313:93,879,839C/T—likely benign
rs74587918913:93,879,841G/C—likely benign
rs77399524913:93,879,850C/T—uncertain significance
rs56180835613:93,879,880G/A—likely benign
rs20159095313:93,883,687T/G——
rs132836513:93,885,830C/Gintron variant—
rs111626013:93,890,670G/Aregulatory region variant—
rs477372413:93,891,889G/C——
rs100899313:93,895,342C/Tintron variant—
rs952398113:93,902,584C/Tintron variant—
rs132836913:93,912,990C/Tregulatory region variant—
rs1183951413:93,938,706A/T——
rs53158268013:93,943,659C/G——
rs14325888113:93,945,858A/Tintron variant—
rs956132913:94,011,169A/Gintron variant—
rs203872613:94,012,100T/Aintron variant—
rs956133113:94,017,476G/T——
rs132397113:94,027,893G/Aintron variant—
rs276208813:94,065,186T/A——
rs7264050413:94,066,952T/Cregulatory region variant—
rs281362013:94,105,937G/Tintron variant—
rs202878913:94,113,389C/G——
rs1285409013:94,197,216A/G—benign
rs118492310213:94,197,509A/G—likely benign
rs88605034913:94,197,512G/T—uncertain significance
rs13827585113:94,197,544A/G—benign
rs77597769513:94,197,547T/C—likely benign
rs75912127313:94,197,550A/G—likely benign
rs75212405013:94,197,558C/G—uncertain significance
rs14387214413:94,197,611T/C—likely benign
rs52891590013:94,197,624C/T—uncertain significance
rs76015020013:94,197,638C/T—uncertain significance
rs129670914413:94,197,639G/A—uncertain significance
rs130730551213:94,197,640C/A—likely benign
rs77635454613:94,197,656A/G—uncertain significance
rs18357697513:94,197,674G/A—uncertain significance
rs19049452713:94,208,649A/T——
rs799831413:94,233,129A/Cintron variant—
rs11565849413:94,259,128A/G—benign
rs384368813:94,283,989C/G—benign
rs384806513:94,283,991A/G—benign
rs958979913:94,284,016A/G—benign
rs7354353813:94,284,219G/T—benign
rs958980713:94,309,026A/G—benign
rs956142813:94,341,096G/Aintron variant—
rs930190613:94,406,339T/A——
rs799521513:94,408,506A/C——
rs451764313:94,417,873A/T——
rs713962613:94,482,224A/G—benign
rs37740440013:94,482,401C/G—uncertain significance
rs141571377613:94,482,403G/T—likely benign
rs75875823213:94,482,416G/A—uncertain significance
rs250207803013:94,482,418G/A—uncertain significance
rs76106190313:94,482,421C/T—uncertain significance
rs76396683013:94,482,463C/T—uncertain significance
rs102853345713:94,482,474C/T—likely benign
rs250207835313:94,482,508G/C—uncertain significance
rs250207839813:94,482,522G/A—likely benign
rs95386702013:94,482,539C/A—uncertain significance
rs213898005113:94,482,540T/G—likely benign
rs144364671813:94,482,542G/C—uncertain significance
rs75983579413:94,482,561G/A—likely benign
rs76322268913:94,482,572A/G—uncertain significance
rs75168233113:94,482,587G/A—uncertain significance
rs20092121513:94,482,597A/G—likely benign
rs76737954713:94,482,598C/T—pathogenic
rs132880272713:94,482,599G/A—uncertain significance
rs77853172013:94,482,635G/T—uncertain significance
rs37197019913:94,482,663A/G—likely benign
rs74618944513:94,482,665A/T—uncertain significance
rs36946706713:94,482,672C/T—uncertain significance
rs76742377913:94,482,681G/A—benign
rs37666591913:94,482,693C/T—likely benign
rs20176100513:94,482,700C/T—uncertain significance

Showing 100 of 311 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.