GPR158
G protein-coupled receptor 158
Summary
Enables G protein-coupled glycine receptor activity and enzyme activator activity. Involved in G protein-coupled receptor signaling pathway; protein localization to plasma membrane; and regulation of G protein-coupled receptor signaling pathway. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants71 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs371970423 | 10:25,464,465 | C/T | — | uncertain significance |
| rs754629829 | 10:25,464,495 | C/T | — | uncertain significance |
| rs1057413193 | 10:25,464,519 | C/T | — | uncertain significance |
| rs771616703 | 10:25,464,618 | A/C | — | uncertain significance |
| rs574076490 | 10:25,464,636 | G/A | — | uncertain significance |
| rs148751649 | 10:25,464,677 | G/A | — | uncertain significance |
| rs775083205 | 10:25,464,690 | C/T | — | uncertain significance |
| rs762987000 | 10:25,464,729 | A/T | — | uncertain significance |
| rs565620071 | 10:25,464,734 | C/A | — | uncertain significance |
| rs757808519 | 10:25,464,759 | A/G | — | uncertain significance |
| rs1395305594 | 10:25,464,761 | G/A | — | likely benign |
| rs762934432 | 10:25,464,833 | T/C | — | likely benign |
| rs1420314133 | 10:25,464,905 | C/G | — | uncertain significance |
| rs535710420 | 10:25,464,915 | A/T | — | uncertain significance |
| rs773101327 | 10:25,464,933 | C/T | — | uncertain significance |
| rs372560108 | 10:25,465,061 | G/A | — | uncertain significance |
| rs750773250 | 10:25,465,149 | C/T | — | uncertain significance |
| rs188462125 | 10:25,465,198 | T/C | — | likely benign |
| rs375860575 | 10:25,465,209 | C/T | — | uncertain significance |
| rs372216544 | 10:25,510,040 | A/G | — | uncertain significance |
| rs59132240 | 10:25,591,153 | A/T | — | — |
| rs71495423 | 10:25,606,005 | C/T | — | — |
| rs369165750 | 10:25,684,867 | G/A | — | uncertain significance |
| rs181041655 | 10:25,684,898 | C/A | — | uncertain significance |
| rs778354003 | 10:25,701,287 | C/G | — | uncertain significance |
| rs2480345 | 10:25,701,341 | G/C | — | benign |
| rs6482479 | 10:25,720,501 | T/C | — | — |
| rs141963368 | 10:25,755,586 | C/T | — | uncertain significance |
| rs774310703 | 10:25,755,587 | G/A | — | uncertain significance |
| rs1329254 | 10:25,767,521 | C/T | intron variant | — |
| rs72786268 | 10:25,770,025 | G/C | intron variant | — |
| rs1360123 | 10:25,773,094 | A/G | intron variant | — |
| rs1536836 | 10:25,790,844 | A/G | intron variant | — |
| rs7077800 | 10:25,819,228 | C/T | intron variant | — |
| rs10764556 | 10:25,819,990 | T/C | intron variant | — |
| rs755687892 | 10:25,839,980 | A/G | — | uncertain significance |
| rs1836719757 | 10:25,840,010 | C/T | — | uncertain significance |
| rs374545502 | 10:25,861,633 | G/A | — | uncertain significance |
| rs2491617098 | 10:25,861,690 | G/A | — | uncertain significance |
| rs200629030 | 10:25,861,742 | G/A | — | uncertain significance |
| rs751398582 | 10:25,861,762 | C/T | — | uncertain significance |
| rs756258435 | 10:25,861,775 | A/G | — | uncertain significance |
| rs190950190 | 10:25,861,787 | T/C | — | uncertain significance |
| rs1837306488 | 10:25,877,960 | G/T | — | uncertain significance |
| rs17558301 | 10:25,880,459 | C/G | intron variant | — |
| rs768516794 | 10:25,883,268 | A/G | — | uncertain significance |
| rs767819600 | 10:25,883,300 | A/C | — | uncertain significance |
| rs1387314771 | 10:25,883,304 | T/C | — | uncertain significance |
| rs367760867 | 10:25,885,597 | G/A | — | uncertain significance |
| rs747271068 | 10:25,885,648 | C/T | — | uncertain significance |
| rs190119414 | 10:25,886,854 | C/T | — | uncertain significance |
| rs752370530 | 10:25,886,984 | G/A | — | uncertain significance |
| rs143609365 | 10:25,887,038 | C/G | — | uncertain significance |
| rs2491656877 | 10:25,887,044 | A/C | — | uncertain significance |
| rs372800397 | 10:25,887,113 | C/T | — | uncertain significance |
| rs774670021 | 10:25,887,271 | A/G | — | uncertain significance |
| rs149419744 | 10:25,887,337 | C/T | — | uncertain significance |
| rs749413527 | 10:25,887,338 | G/A | — | uncertain significance |
| rs1293911390 | 10:25,887,350 | A/G | — | uncertain significance |
| rs755963863 | 10:25,887,467 | A/G | — | uncertain significance |
| rs139042739 | 10:25,887,658 | G/A | — | uncertain significance |
| rs2491659387 | 10:25,887,794 | C/T | — | uncertain significance |
| rs372238950 | 10:25,887,877 | C/A | — | uncertain significance |
| rs376871482 | 10:25,887,941 | C/T | — | uncertain significance |
| rs754137888 | 10:25,887,963 | A/C | — | uncertain significance |
| rs375852204 | 10:25,887,965 | T/C | — | uncertain significance |
| rs147110255 | 10:25,888,010 | G/A | — | uncertain significance |
| rs199660896 | 10:25,888,013 | G/A | — | uncertain significance |
| rs372046524 | 10:25,888,058 | G/A | — | uncertain significance |
| rs138571905 | 10:25,888,093 | G/C | — | uncertain significance |
| rs2491660367 | 10:25,888,132 | T/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.