rs7077800
This is a intron variant variant in the GPR158 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
diverticular disease
Schafmayer C et al. “Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.” Gut 68(5):854-865 (2019)
Allele C
OR 1.08
p 2.0e-22
N 451,099
Large GWAS
European
About GPR158
Enables G protein-coupled glycine receptor activity and enzyme activator activity. Involved in G protein-coupled receptor signaling pathway; protein localization to plasma membrane; and regulation of G protein-coupled receptor signaling pathway. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all GPR158 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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