GRIN3B

glutamate ionotropic receptor NMDA type subunit 3B

Summary

The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia. [provided by RefSeq, Nov 2015]

Known Variants119 total

rsidPosition (GRCh37)AllelesClassClinVar
rs11274375319:1,000,420A/G—benign
rs117767411819:1,000,524C/G—uncertain significance
rs103700653119:1,000,566C/T—uncertain significance
rs146715630219:1,000,584C/T—uncertain significance
rs99805375819:1,000,600C/T—uncertain significance
rs134211923219:1,000,612G/A—uncertain significance
rs148165532719:1,000,648G/T—uncertain significance
rs54682331319:1,000,676C/A—likely benign
rs251208726919:1,000,681G/A—uncertain significance
rs136721359019:1,000,689G/A—uncertain significance
rs129091153919:1,000,777T/C—uncertain significance
rs1298600219:1,000,785C/T—benign
rs76409911619:1,000,786A/T—uncertain significance
rs140344379619:1,000,803A/G—uncertain significance
rs11588288019:1,001,777C/Aregulatory region variant—
rs76888780119:1,003,141C/G—uncertain significance
rs136939614319:1,003,222G/C—uncertain significance
rs37572454919:1,003,321C/T—uncertain significance
rs37003153519:1,003,324C/T—uncertain significance
rs19981997219:1,003,349G/A—likely benign
rs77406114919:1,003,364C/T—uncertain significance
rs36832947919:1,003,370C/T—uncertain significance
rs36870339619:1,003,373C/T—uncertain significance
rs76015658819:1,003,432C/T—uncertain significance
rs75486321519:1,003,496C/T—uncertain significance
rs130941418319:1,003,528C/T—uncertain significance
rs103054175319:1,003,568T/G—uncertain significance
rs77876981819:1,003,607G/A—uncertain significance
rs203870804119:1,003,637C/T—uncertain significance
rs57358855419:1,003,672G/A—uncertain significance
rs90903562019:1,003,682A/C—conflicting classifications of pathogenicity
rs94861599519:1,003,685C/T—uncertain significance
rs74862571719:1,003,690G/C—uncertain significance
rs104364580619:1,003,708C/T—uncertain significance
rs88999767119:1,003,720C/T—uncertain significance
rs57741369519:1,003,721G/A—uncertain significance
rs251209213519:1,004,536T/A—uncertain significance
rs76035893519:1,004,621G/A—uncertain significance
rs37118422419:1,004,632C/T—uncertain significance
rs7466791319:1,004,633G/A—uncertain significance
rs37099569219:1,004,668C/T—uncertain significance
rs76601884819:1,004,672A/G—uncertain significance
rs37564581419:1,004,674G/A—uncertain significance
rs74955108419:1,004,708C/T—uncertain significance
rs7682701319:1,004,709A/G—benign
rs14752145219:1,004,773C/T—uncertain significance
rs20163838019:1,004,803G/A—uncertain significance
rs76006793919:1,004,843C/G—uncertain significance
rs1066658319:1,004,896———
rs76777865019:1,004,957G/A—uncertain significance
rs77469978419:1,004,983T/C—uncertain significance
rs76284476919:1,005,002G/A—uncertain significance
rs78095229719:1,005,007G/A—uncertain significance
rs251209299419:1,005,037T/C—uncertain significance
rs74742823819:1,005,071G/A—uncertain significance
rs77119386719:1,005,076C/T—uncertain significance
rs78147949519:1,005,083C/T—uncertain significance
rs76020123019:1,005,113G/A—uncertain significance
rs20076450719:1,005,136A/G—uncertain significance
rs74943794319:1,005,172C/T—uncertain significance
rs14348906719:1,005,178C/T—uncertain significance
rs52969741619:1,005,179G/A—uncertain significance
rs6174028519:1,005,186G/A—benign
rs98135295519:1,005,193C/A—uncertain significance
rs56660327719:1,005,199G/C—uncertain significance
rs75766481319:1,005,202G/A—uncertain significance
rs251209329719:1,005,205T/C—uncertain significance
rs138825199719:1,005,227C/A—uncertain significance
rs224015819:1,005,230T/C—benign
rs76933504119:1,005,248C/A—uncertain significance
rs76538570219:1,005,311C/T—uncertain significance
rs14525371319:1,005,328C/T—uncertain significance
rs76004944519:1,005,373G/A—uncertain significance
rs14184497019:1,005,389G/A—uncertain significance
rs54188470419:1,005,394G/A—uncertain significance
rs77837724319:1,005,422C/T—uncertain significance
rs1297394819:1,005,531G/Tsynonymous variant—
rs251209576319:1,007,632C/A—uncertain significance
rs37108651819:1,007,663G/C—uncertain significance
rs74717978819:1,007,688A/G—uncertain significance
rs137992831519:1,007,738G/C—uncertain significance
rs141816222819:1,007,739C/T—uncertain significance
rs76396788719:1,007,751C/T—uncertain significance
rs136641327519:1,007,756G/A—uncertain significance
rs53736439719:1,007,769T/G—uncertain significance
rs14443298819:1,007,862C/G—uncertain significance
rs14840683119:1,007,866C/A—likely benign
rs251209663919:1,007,898C/G—uncertain significance
rs145007260119:1,007,941T/G—uncertain significance
rs203878076619:1,008,187C/G—uncertain significance
rs37454288119:1,008,189G/A—uncertain significance
rs251209746019:1,008,214C/G—uncertain significance
rs104831648519:1,008,258C/T—uncertain significance
rs76177181519:1,008,269G/T—uncertain significance
rs75579863819:1,008,273G/A—uncertain significance
rs6174437519:1,008,704G/A—benign
rs76699157919:1,008,744A/C—uncertain significance
rs138122301319:1,008,749A/G—uncertain significance
rs98717978519:1,008,882G/T—uncertain significance
rs124151207419:1,008,893G/A—uncertain significance

Showing 100 of 119 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.