GSTA5
glutathione S-transferase alpha 5
Summary
The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).[supplied by OMIM, Sep 2008]
Known Variants18 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2532742085 | 6:52,696,716 | G/C | — | uncertain significance |
| rs2532742146 | 6:52,696,740 | G/A | — | uncertain significance |
| rs538519116 | 6:52,696,866 | C/T | — | — |
| rs55815585 | 6:52,697,601 | T/C | — | — |
| rs1764236372 | 6:52,697,659 | T/C | — | uncertain significance |
| rs1764237425 | 6:52,697,726 | G/C | — | uncertain significance |
| rs747083239 | 6:52,697,740 | A/G | — | likely benign |
| rs1448259601 | 6:52,697,754 | C/A | — | uncertain significance |
| rs766876198 | 6:52,697,768 | T/G | — | uncertain significance |
| rs764930349 | 6:52,698,989 | C/G | — | uncertain significance |
| rs1764259528 | 6:52,699,001 | C/G | — | uncertain significance |
| rs372635261 | 6:52,701,087 | G/T | — | uncertain significance |
| rs771818589 | 6:52,701,103 | G/T | — | uncertain significance |
| rs1322103924 | 6:52,701,137 | T/C | — | uncertain significance |
| rs9382146 | 6:52,702,085 | G/T | — | — |
| rs4144185 | 6:52,702,948 | A/G | intron variant | — |
| rs777093478 | 6:52,705,554 | G/A | — | uncertain significance |
| rs751102351 | 6:52,705,557 | T/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.