Trait
SNPs associated with Psoriatic arthritis
35 genetic variants across 18 genes have been associated with Psoriatic arthritis in published research. Key genes include C1orf141, F10, FAM8A1.
Associated variants35 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs11209026 | IL23R | Protective against psoriatic arthritis risk | Meta-analysis |
| rs1811198 | — | GWAS association (p=4.0e-103) | Major Consortium Study |
| rs33980500 | TRAF3IP2 | GWAS association (p=1.0e-36) | Major Consortium Study |
| rs146571698 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs372925782 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs538519116 | GSTA5 | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs574176611 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs577898960 | F10 | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs181120299 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs567050291 | SLC22A23 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs11085727 | TYK2 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs77569865 | SCYL1 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs550235695 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs551907784 | GNG4 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs73971815 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs200868187 | FAM8A1 | GWAS association (p=5.0e-40) | Major Consortium Study |
| rs28998802 | — | GWAS association (p=6.0e-17) | Major Consortium Study |
| rs918520 | — | GWAS association (p=7.0e-34) | Major Consortium Study |
| rs12191877 | — | GWAS association (p=2.0e-99) | Large GWAS |
| rs13191343 | HLA-C | GWAS association (p=2.0e-72) | Large GWAS |
| rs10484554 | HLA-C | Higher risk of psoriatic arthritis | Large GWAS |
| rs62377586 | LOC285626 | GWAS association (p=8.0e-35) | Large GWAS |
| rs4921482 | LOC285626 | GWAS association (p=1.0e-24) | Large GWAS |
| rs76956521 | TNIP1 | GWAS association (p=3.0e-23) | Large GWAS |
| rs2111485 | LOC105373724 | GWAS association (p=1.0e-20) | Large GWAS |
| rs12044149 | C1orf141 | GWAS association (p=4.0e-20) | Large GWAS |
| rs12188300 | — | GWAS association (p=7.0e-17) | Large GWAS |
| rs848 | IL13 | GWAS association (p=9.0e-16) | Large GWAS |
| rs34536443 | TYK2 | GWAS association (p=1.0e-14) | Large GWAS |
| rs17622208 | SLC22A5 | GWAS association (p=6.0e-14) | Large GWAS |
| rs2020854 | STAT2 | GWAS association (p=1.0e-13) | Large GWAS |
| rs3794767 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs1395621 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs5754467 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs610604 | TNFAIP3 | GWAS association (p=8.0e-09) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.