rs200868187
This is a protein-altering variant in the FAM8A1 gene.
▶GWAS Catalog Trait Associations (14)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (14)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
psoriasis vulgaris
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.58
p 4.0e-98
N 444,887
Major Consortium StudyLarge GWAS
European
leukocyte quantity
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.07
p 3.0e-18
N 381,099
Major Consortium StudyLarge GWAS
European
platelet volume
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.07
p 1.0e-17
N 335,593
Major Consortium StudyLarge GWAS
European
macular degeneration
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.18
p 4.0e-14
N 439,724
Major Consortium StudyLarge GWAS
European
erythematosquamous dermatosis
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.17
p 5.0e-14
N 425,227
Major Consortium StudyLarge GWAS
European
basophil measurement
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.08
p 7.0e-14
N 158,583
Major Consortium StudyLarge GWAS
European
seborrheic dermatitis
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.16
p 5.0e-13
N 425,845
Major Consortium StudyLarge GWAS
European
drug use measurement, skin disease
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.22
p 8.0e-15
N 404,034
Major Consortium StudyLarge GWAS
multi-ancestry
eosinophil count
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.09
p 2.0e-19
N 447,366
Major Consortium StudyLarge GWAS
multi-ancestry
monocyte count
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.06
p 2.0e-14
N 296,975
Major Consortium StudyLarge GWAS
European
About FAM8A1
Predicted to be involved in ERAD pathway. Part of Hrd1p ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM8A1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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