Trait
SNPs associated with Macular Degeneration
30 genetic variants across 18 genes have been associated with Macular Degeneration in published research. Key genes include APOE, ARMS2, C3.
Associated variants30 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3043084 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs1329424 | CFH | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs61871744 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs579745 | CFH | GWAS association (p=6.0e-312) | Major Consortium Study |
| rs36212732 | ARMS2 | GWAS association (p=6.0e-239) | Major Consortium Study |
| rs10490924 | ARMS2 | GWAS association (p=7.0e-218) | Major Consortium Study |
| rs2230199 | C3 | GWAS association (p=2.0e-94) | Major Consortium Study |
| rs1129038 | HERC2 | GWAS association (p=1.0e-52) | Major Consortium Study |
| rs3816117 | CETP | GWAS association (p=1.0e-32) | Major Consortium Study |
| rs4711751 | POLR1C | GWAS association (p=5.0e-32) | Major Consortium Study |
| rs34882957 | C9 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs11200630 | LOC105378525 | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=3.0e-20) | Major Consortium Study |
| rs485741 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs3138141 | RDH5 | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs56075814 | MIR29B2 | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs11628653 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs135173 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs200868187 | FAM8A1 | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs7758685 | — | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs1036106293 | NLRP4 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs4844393 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs3812111 | COL10A1 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs2466572 | CD46 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs2025704 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs141853578 | CFI | GWAS association (p=9.0e-27) | Major Consortium Study |
| rs56156922 | — | GWAS association (p=1.0e-26) | Major Consortium Study |
| rs429608 | SKIV2L | GWAS association (p=4.0e-110) | Major Consortium Study |
| rs75139357 | — | GWAS association (p=3.0e-09) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.