IL23R

interleukin 23 receptor

Summary

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]

Known Variants299 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs74801462	1:67,604,296	T/C	intron variant	—
rs10789226	1:67,623,728	A/T	—	—
rs117633859	1:67,627,828	A/G	upstream gene variant	—
rs6682925	1:67,631,262	C/A	—	—
rs11465754	1:67,631,431	A/G	upstream gene variant	—
rs756938673	1:67,633,811	A/G	—	uncertain significance
rs1884444	1:67,633,812	G/T	missense variant	benign
rs144070297	1:67,633,830	T/G	—	uncertain significance
rs769230441	1:67,633,831	G/A	—	uncertain significance
rs2102553806	1:67,633,842	C/T	—	likely benign
rs761754539	1:67,633,849	A/G	—	uncertain significance
rs185697788	1:67,633,858	A/G	—	uncertain significance
rs2525198587	1:67,633,861	T/C	—	uncertain significance
rs765086515	1:67,633,862	G/T	—	uncertain significance
rs763952944	1:67,633,879	G/A	—	uncertain significance
rs2525198716	1:67,633,889	T/C	—	likely benign
rs201919502	1:67,633,893	T/A	—	likely benign
rs11465770	1:67,633,963	C/T	intron variant	—
rs2525202657	1:67,635,041	C/T	—	likely benign
rs2525202689	1:67,635,052	A/G	—	uncertain significance
rs1455151608	1:67,635,053	C/T	—	likely benign
rs1156783916	1:67,635,054	A/C	—	uncertain significance
rs1384135313	1:67,635,058	G/A	—	uncertain significance
rs1396700760	1:67,635,059	G/T	—	uncertain significance
rs2525202778	1:67,635,060	G/A	—	uncertain significance
rs762697123	1:67,635,065	A/G	—	likely benign
rs2102555960	1:67,635,076	T/A	—	uncertain significance
rs766991367	1:67,635,102	A/G	—	uncertain significance
rs749888878	1:67,635,104	A/C	—	likely benign
rs2525202946	1:67,635,115	C/T	—	uncertain significance
rs539781624	1:67,635,117	G/A	—	uncertain significance
rs754273325	1:67,635,119	A/G	—	likely benign
rs767092630	1:67,635,120	A/T	—	uncertain significance
rs777730388	1:67,635,137	A/G	—	likely benign
rs1469323792	1:67,635,141	A/G	—	uncertain significance
rs2525203117	1:67,635,151	T/A	—	uncertain significance
rs1306650296	1:67,635,161	T/C	—	likely benign
rs1425917268	1:67,635,164	C/T	—	likely benign
rs1171441053	1:67,635,173	A/G	—	likely benign
rs2525203208	1:67,635,182	A/G	—	likely benign
rs368811377	1:67,635,191	G/A	—	likely benign
rs138312673	1:67,635,194	T/A	—	likely benign
rs2525203281	1:67,635,199	A/T	—	uncertain significance
rs1646915405	1:67,635,200	A/C	—	uncertain significance
rs11465779	1:67,635,206	A/C	—	likely benign
rs749929021	1:67,635,210	C/T	—	uncertain significance
rs76575803	1:67,635,211	G/A	—	likely benign
rs753589961	1:67,635,212	G/A	—	likely benign
rs1646915882	1:67,635,213	C/T	—	uncertain significance
rs2525203454	1:67,635,226	A/G	—	uncertain significance
rs754677847	1:67,635,230	T/C	—	likely benign
rs757367045	1:67,635,276	C/T	—	uncertain significance
rs1646916754	1:67,635,277	A/G	—	uncertain significance
rs2102556377	1:67,635,292	T/C	—	uncertain significance
rs1490465214	1:67,635,293	G/A	—	likely benign
rs1646917043	1:67,635,298	G/A	—	uncertain significance
rs2525203859	1:67,635,306	G/C	—	uncertain significance
rs2525203878	1:67,635,312	T/A	—	uncertain significance
rs540500252	1:67,635,333	G/T	—	likely benign
rs11465780	1:67,635,341	T/C	—	benign
rs11465788	1:67,648,294	C/G	—	—
rs6687620	1:67,648,460	T/C	—	benign
rs111740171	1:67,648,503	T/C	—	likely benign
rs2525254378	1:67,648,506	T/C	—	likely benign
rs2525254395	1:67,648,508	T/G	—	likely benign
rs781262110	1:67,648,522	C/T	—	uncertain significance
rs143803981	1:67,648,523	G/A	—	benign
rs539497366	1:67,648,538	T/A	—	uncertain significance
rs773141807	1:67,648,546	C/T	—	uncertain significance
rs747004464	1:67,648,553	C/A	—	likely benign
rs770937631	1:67,648,559	T/C	—	likely benign
rs1182846342	1:67,648,585	C/T	—	uncertain significance
rs76418789	1:67,648,596	G/A	missense variant	benign
rs775258971	1:67,648,600	A/C	—	uncertain significance
rs776235812	1:67,648,602	C/T	—	uncertain significance
rs200641318	1:67,648,616	C/T	—	likely benign
rs75811765	1:67,648,625	C/T	—	benign
rs555691349	1:67,648,626	G/A	—	uncertain significance
rs149318636	1:67,648,627	T/A	—	uncertain significance
rs201902670	1:67,648,630	T/C	—	uncertain significance
rs376377228	1:67,648,633	A/G	—	uncertain significance
rs75363634	1:67,648,659	C/T	—	likely benign
rs2064689	1:67,653,010	G/A	intron variant	—
rs17375018	1:67,655,147	G/C	—	—
rs61780312	1:67,661,648	T/G	upstream gene variant	—
rs779240654	1:67,666,403	T/G	—	likely benign
rs1648567458	1:67,666,405	T/C	—	likely benign
rs201733302	1:67,666,407	T/G	—	likely benign
rs757169560	1:67,666,409	T/G	—	likely benign
rs546101785	1:67,666,411	T/C	—	likely benign
rs1441177286	1:67,666,412	G/T	—	likely benign
rs1282657856	1:67,666,423	A/T	—	uncertain significance
rs769559634	1:67,666,433	G/A	—	uncertain significance
rs371531867	1:67,666,445	T/C	—	uncertain significance
rs1036802029	1:67,666,467	A/G	—	uncertain significance
rs1648573610	1:67,666,471	C/T	—	likely benign
rs766732453	1:67,666,483	A/G	—	likely benign
rs2525327092	1:67,666,504	C/T	—	likely benign
rs1558240308	1:67,666,506	T/C	—	uncertain significance
rs146440064	1:67,666,507	G/T	—	uncertain significance

Showing 100 of 299 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.