HCRTR1
hypocretin receptor 1
Summary
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]
Known Variants41 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11589306 | 1:32,082,822 | C/G | upstream gene variant | — |
| rs1313372688 | 1:32,084,804 | C/T | — | uncertain significance |
| rs2521855725 | 1:32,084,826 | G/A | — | likely benign |
| rs1557575618 | 1:32,084,840 | G/T | — | uncertain significance |
| rs199831745 | 1:32,084,875 | G/A | — | uncertain significance |
| rs775286747 | 1:32,084,987 | C/T | — | uncertain significance |
| rs77293616 | 1:32,085,143 | C/T | — | benign |
| rs201319457 | 1:32,085,144 | G/A | — | uncertain significance |
| rs144638017 | 1:32,085,151 | G/A | — | uncertain significance |
| rs765816307 | 1:32,085,163 | T/C | — | uncertain significance |
| rs111252644 | 1:32,085,170 | A/G | — | benign |
| rs1639808864 | 1:32,085,193 | A/G | — | uncertain significance |
| rs545611444 | 1:32,085,252 | G/A | — | uncertain significance |
| rs772997908 | 1:32,085,276 | G/A | — | uncertain significance |
| rs968335 | 1:32,085,776 | G/T | — | — |
| rs2521863894 | 1:32,086,483 | A/G | — | uncertain significance |
| rs202061731 | 1:32,086,543 | C/T | — | uncertain significance |
| rs919621513 | 1:32,086,603 | G/A | — | uncertain significance |
| rs752681555 | 1:32,086,649 | G/A | — | uncertain significance |
| rs199860096 | 1:32,087,104 | A/G | — | uncertain significance |
| rs777211156 | 1:32,087,128 | C/G | — | uncertain significance |
| rs374843159 | 1:32,089,127 | C/A | — | uncertain significance |
| rs187526271 | 1:32,089,151 | C/T | — | uncertain significance |
| rs144550848 | 1:32,089,152 | G/A | — | uncertain significance |
| rs140296272 | 1:32,089,208 | G/A | — | uncertain significance |
| rs7516785 | 1:32,089,221 | G/A | — | benign |
| rs1345639549 | 1:32,089,283 | C/A | — | uncertain significance |
| rs776437941 | 1:32,089,331 | G/A | — | uncertain significance |
| rs772642320 | 1:32,089,344 | T/C | — | uncertain significance |
| rs547684510 | 1:32,089,360 | C/T | — | likely benign |
| rs139306009 | 1:32,090,600 | T/C | — | uncertain significance |
| rs541388873 | 1:32,090,614 | C/T | — | uncertain significance |
| rs200961371 | 1:32,090,615 | G/A | — | uncertain significance |
| rs181149943 | 1:32,090,716 | A/G | — | uncertain significance |
| rs6663012 | 1:32,091,779 | T/G | downstream gene variant | — |
| rs202193411 | 1:32,092,400 | G/A | — | uncertain significance |
| rs142508339 | 1:32,092,408 | T/C | — | uncertain significance |
| rs1035124863 | 1:32,092,427 | G/A | — | uncertain significance |
| rs2271933 | 1:32,092,525 | A/G | missense variant | — |
| rs377345441 | 1:32,092,561 | G/A | — | uncertain significance |
| rs10798879 | 1:32,096,815 | T/C | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.