IFI35
interferon induced protein 35
Summary
Enables identical protein binding activity. Involved in several processes, including macrophage activation involved in immune response; negative regulation of non-canonical NF-kappaB signal transduction; and positive regulation of defense response. Located in several cellular components, including cytosol; extracellular space; and nuclear lumen. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants30 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs138234610 | 17:41,158,975 | C/T | — | uncertain significance |
| rs8070922 | 17:41,162,339 | G/A | downstream gene variant | — |
| rs777691679 | 17:41,164,274 | G/A | — | likely benign |
| rs780267427 | 17:41,165,101 | G/A | — | uncertain significance |
| rs200866570 | 17:41,165,121 | C/G | — | uncertain significance |
| rs368042561 | 17:41,165,140 | T/C | — | uncertain significance |
| rs1597780493 | 17:41,165,149 | A/G | — | uncertain significance |
| rs374815335 | 17:41,165,317 | C/A | — | likely benign |
| rs376682517 | 17:41,165,344 | G/A | — | uncertain significance |
| rs149709197 | 17:41,165,514 | C/T | — | uncertain significance |
| rs780997177 | 17:41,165,548 | T/C | — | uncertain significance |
| rs1192224414 | 17:41,165,565 | G/C | — | uncertain significance |
| rs1260942379 | 17:41,165,566 | A/T | — | uncertain significance |
| rs377676655 | 17:41,165,576 | C/G | — | uncertain significance |
| rs145567403 | 17:41,165,587 | T/C | — | uncertain significance |
| rs760145503 | 17:41,165,590 | T/A | — | uncertain significance |
| rs769757979 | 17:41,165,591 | C/G | — | uncertain significance |
| rs909534000 | 17:41,165,595 | G/A | — | uncertain significance |
| rs369228705 | 17:41,165,631 | C/T | — | uncertain significance |
| rs150695787 | 17:41,165,632 | G/A | — | likely benign |
| rs755531972 | 17:41,165,816 | G/A | — | uncertain significance |
| rs200811245 | 17:41,165,868 | C/T | — | uncertain significance |
| rs13229 | 17:41,165,878 | C/T | synonymous variant | — |
| rs773873458 | 17:41,166,152 | G/A | — | uncertain significance |
| rs765602573 | 17:41,166,171 | C/G | — | uncertain significance |
| rs376575632 | 17:41,166,174 | A/G | — | uncertain significance |
| rs201486546 | 17:41,166,189 | C/T | — | uncertain significance |
| rs2544354627 | 17:41,166,227 | C/G | — | uncertain significance |
| rs762451969 | 17:41,166,263 | G/C | — | uncertain significance |
| rs375429330 | 17:41,166,266 | G/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.