IFITM2
interferon induced transmembrane protein 2
Summary
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2. [provided by RefSeq, Nov 2021]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs7480524 | 11:307,696 | T/A | — | — |
| rs7481219 | 11:307,808 | A/T | — | — |
| rs3888187 | 11:307,961 | A/C | regulatory region variant | — |
| rs4029213 | 11:307,972 | T/C | regulatory region variant | — |
| rs28521954 | 11:307,999 | T/G | regulatory region variant | — |
| rs992576962 | 11:308,214 | T/C | — | uncertain significance |
| rs376647548 | 11:308,270 | G/C | — | likely benign |
| rs2539172158 | 11:308,289 | G/A | — | uncertain significance |
| rs1564848506 | 11:308,295 | C/T | — | uncertain significance |
| rs14408 | 11:308,314 | T/A | missense variant | — |
| rs761775091 | 11:308,315 | G/A | — | uncertain significance |
| rs747098995 | 11:308,340 | G/A | — | uncertain significance |
| rs1058935 | 11:308,363 | G/T | synonymous variant | — |
| rs536665329 | 11:308,391 | A/G | — | uncertain significance |
| rs771775579 | 11:308,433 | G/A | — | uncertain significance |
| rs909097 | 11:308,576 | G/A | regulatory region variant | — |
| rs2539172837 | 11:309,041 | T/C | — | uncertain significance |
| rs770068982 | 11:309,133 | A/C | — | uncertain significance |
| rs767126291 | 11:309,148 | G/C | — | uncertain significance |
| rs376286409 | 11:309,161 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.