rs7481219

This variant is located in the IFITM2 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain physiology trait

Lee S et al. “Amplitudes of resting-state functional networks - investigation into their correlates and biophysical properties.” Neuroimage 265:119779 (2023)

Allele A

OR —

β 0.065

p 5.0e-10

N 22,172

Large GWAS

European

sex hormone-binding globulin measurement

Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)

Allele A

OR 0.01

p 4.0e-9

N 189,473

Large GWAS

European

About IFITM2

Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2. [provided by RefSeq, Nov 2021]

View all IFITM2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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