IL17F

interleukin 17F

Summary

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

Known Variants139 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1953325	6:52,101,486	A/C	—	benign
rs11465554	6:52,101,593	T/C	—	benign
rs189630805	6:52,101,606	G/A	—	benign
rs1169477692	6:52,101,732	C/G	—	uncertain significance
rs571639953	6:52,101,733	T/C	—	uncertain significance
rs767197513	6:52,101,738	A/G	—	likely benign
rs763780	6:52,101,739	T/C	missense variant	benign
rs2532686870	6:52,101,742	T/C	—	likely benign
rs149025136	6:52,101,744	G/T	—	likely benign
rs144576902	6:52,101,752	G/A	—	uncertain significance
rs11465553	6:52,101,758	C/T	missense variant	benign
rs780312510	6:52,101,759	G/A	—	likely benign
rs1414979462	6:52,101,762	G/A	—	likely benign
rs769299818	6:52,101,763	G/A	—	uncertain significance
rs1345707985	6:52,101,765	G/A	—	conflicting classifications of pathogenicity
rs1446649876	6:52,101,774	A/T	—	likely benign
rs1763973005	6:52,101,784	A/C	—	uncertain significance
rs774103459	6:52,101,793	A/C	—	uncertain significance
rs1015495067	6:52,101,794	A/G	—	conflicting classifications of pathogenicity
rs1173562555	6:52,101,808	G/C	—	uncertain significance
rs1396005309	6:52,101,810	G/A	—	likely benign
rs2532687050	6:52,101,817	T/C	—	uncertain significance
rs969467406	6:52,101,818	G/C	—	uncertain significance
rs2532687056	6:52,101,819	G/C	—	uncertain significance
rs764026426	6:52,101,829	C/T	—	uncertain significance
rs147873628	6:52,101,830	G/A	—	uncertain significance
rs141798304	6:52,101,833	C/T	—	conflicting classifications of pathogenicity
rs765197624	6:52,101,834	G/A	—	likely benign
rs780259967	6:52,101,841	G/T	—	uncertain significance
rs2397084	6:52,101,844	T/C	missense variant	benign
rs755388522	6:52,101,846	T/C	—	likely benign
rs1763976446	6:52,101,847	T/C	—	uncertain significance
rs550486674	6:52,101,860	C/T	—	uncertain significance
rs536968854	6:52,101,861	G/A	—	likely benign
rs1763977355	6:52,101,869	T/G	—	uncertain significance
rs2532687204	6:52,101,870	G/A	—	likely benign
rs767452983	6:52,101,871	G/T	—	uncertain significance
rs1042175463	6:52,101,874	A/C	—	uncertain significance
rs137981743	6:52,101,876	G/T	—	uncertain significance
rs2532687287	6:52,101,892	G/A	—	uncertain significance
rs148940532	6:52,101,903	G/A	—	benign
rs766577007	6:52,101,913	C/T	—	uncertain significance
rs2532687364	6:52,101,916	C/T	—	uncertain significance
rs1325665616	6:52,101,923	C/A	—	uncertain significance
rs2128267440	6:52,101,930	A/G	—	likely benign
rs1232602156	6:52,101,933	T/C	—	likely benign
rs748486078	6:52,101,937	G/A	missense variant	uncertain significance
rs376780230	6:52,101,946	C/T	—	uncertain significance
rs142962486	6:52,101,947	G/A	—	uncertain significance
rs775184787	6:52,101,948	G/C	—	uncertain significance
rs746645424	6:52,101,951	G/A	—	likely benign
rs2128267452	6:52,101,963	G/T	—	likely benign
rs113299618	6:52,101,969	G/A	—	uncertain significance
rs972404643	6:52,101,971	A/G	—	likely benign
rs1274464224	6:52,101,973	G/A	—	likely benign
rs374838092	6:52,101,975	G/A	—	likely benign
rs754360019	6:52,103,518	T/C	—	uncertain significance
rs571390206	6:52,103,523	C/A	—	uncertain significance
rs117796773	6:52,103,527	C/A	—	conflicting classifications of pathogenicity
rs747960305	6:52,103,528	G/A	—	uncertain significance
rs769617558	6:52,103,539	G/C	—	conflicting classifications of pathogenicity
rs530331585	6:52,103,541	G/A	—	uncertain significance
rs376671742	6:52,103,547	T/G	—	uncertain significance
rs1764012735	6:52,103,549	G/T	—	uncertain significance
rs371280410	6:52,103,552	C/T	—	uncertain significance
rs770953888	6:52,103,553	G/T	—	uncertain significance
rs373228601	6:52,103,559	C/T	—	uncertain significance
rs6931727	6:52,103,560	G/A	—	benign
rs144854652	6:52,103,567	C/T	—	conflicting classifications of pathogenicity
rs764500129	6:52,103,568	G/A	—	uncertain significance
rs764517083	6:52,103,574	T/C	—	uncertain significance
rs569473195	6:52,103,580	C/T	—	conflicting classifications of pathogenicity
rs751070725	6:52,103,581	G/A	—	likely benign
rs1235526621	6:52,103,582	C/T	—	uncertain significance
rs754476266	6:52,103,583	G/T	—	uncertain significance
rs780766050	6:52,103,594	T/C	—	uncertain significance
rs2532689574	6:52,103,600	A/T	—	uncertain significance
rs1488403842	6:52,103,601	T/C	—	uncertain significance
rs2128267796	6:52,103,602	G/T	—	likely benign
rs1433771627	6:52,103,605	A/G	—	likely benign
rs889879171	6:52,103,608	G/A	—	likely benign
rs748990409	6:52,103,623	A/G	—	likely benign
rs759760136	6:52,103,638	C/G	—	likely benign
rs772268344	6:52,103,640	G/A	—	uncertain significance
rs760922852	6:52,103,642	C/A	—	uncertain significance
rs1442309467	6:52,103,645	C/T	—	uncertain significance
rs535783581	6:52,103,648	T/C	—	uncertain significance
rs1238529220	6:52,103,649	C/T	—	uncertain significance
rs1331321771	6:52,103,652	G/A	—	uncertain significance
rs1764016998	6:52,103,657	T/A	—	uncertain significance
rs1582260865	6:52,103,659	G/C	—	uncertain significance
rs1764017239	6:52,103,661	A/T	—	uncertain significance
rs1005482869	6:52,103,666	G/A	—	uncertain significance
rs1436156723	6:52,103,667	T/C	—	uncertain significance
rs1192851440	6:52,103,668	A/G	—	likely benign
rs555372013	6:52,103,670	G/A	—	uncertain significance
rs1582260891	6:52,103,671	T/C	—	likely benign
rs750915214	6:52,103,678	T/C	—	uncertain significance
rs2532689811	6:52,103,680	G/C	—	likely benign
rs2532689817	6:52,103,681	G/A	—	uncertain significance

Showing 100 of 139 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.