IL22RA1
interleukin 22 receptor subunit alpha 1
Summary
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
Known Variants58 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3795300 | 1:24,447,214 | G/A | — | benign |
| rs1418855595 | 1:24,447,300 | A/G | — | uncertain significance |
| rs1284015340 | 1:24,447,452 | G/A | — | uncertain significance |
| rs3795299 | 1:24,447,468 | G/C | missense variant | benign |
| rs142012185 | 1:24,447,494 | A/T | — | uncertain significance |
| rs1352455427 | 1:24,447,521 | G/A | — | uncertain significance |
| rs1237547042 | 1:24,447,525 | G/A | — | uncertain significance |
| rs769939635 | 1:24,447,557 | G/A | — | uncertain significance |
| rs1644117740 | 1:24,447,668 | G/T | — | uncertain significance |
| rs761786806 | 1:24,447,725 | T/C | — | uncertain significance |
| rs1644118202 | 1:24,447,731 | T/G | — | uncertain significance |
| rs2522986789 | 1:24,447,746 | A/T | — | uncertain significance |
| rs35401673 | 1:24,447,801 | T/C | — | benign |
| rs959104634 | 1:24,447,807 | C/T | — | uncertain significance |
| rs143412406 | 1:24,447,832 | C/T | — | benign |
| rs140471465 | 1:24,447,867 | C/A | — | uncertain significance |
| rs750435511 | 1:24,447,939 | G/A | — | uncertain significance |
| rs139839650 | 1:24,447,988 | C/A | — | uncertain significance |
| rs745331292 | 1:24,448,002 | C/T | — | likely benign |
| rs149851427 | 1:24,448,067 | C/T | — | uncertain significance |
| rs17852648 | 1:24,448,084 | G/A | — | benign |
| rs2522988503 | 1:24,448,101 | A/G | — | uncertain significance |
| rs1171724848 | 1:24,448,111 | C/A | — | uncertain significance |
| rs771280024 | 1:24,448,176 | C/T | — | uncertain significance |
| rs2522988793 | 1:24,448,187 | A/C | — | uncertain significance |
| rs780540586 | 1:24,448,199 | G/T | — | uncertain significance |
| rs1440726523 | 1:24,448,214 | A/T | — | uncertain significance |
| rs141305131 | 1:24,448,217 | C/T | — | uncertain significance |
| rs750881925 | 1:24,449,808 | G/A | — | uncertain significance |
| rs769969480 | 1:24,449,827 | A/G | — | uncertain significance |
| rs538329296 | 1:24,449,887 | C/T | — | uncertain significance |
| rs781318276 | 1:24,449,910 | C/T | — | uncertain significance |
| rs16829204 | 1:24,454,688 | C/T | — | benign |
| rs757272300 | 1:24,460,774 | C/T | — | likely benign |
| rs747331946 | 1:24,460,790 | C/T | — | uncertain significance |
| rs17852649 | 1:24,460,797 | T/G | — | benign |
| rs1420565670 | 1:24,460,801 | G/A | — | uncertain significance |
| rs750958828 | 1:24,460,813 | T/C | — | uncertain significance |
| rs34900099 | 1:24,460,844 | A/G | — | benign |
| rs144874898 | 1:24,460,847 | T/C | — | uncertain significance |
| rs534408154 | 1:24,460,856 | C/T | — | uncertain significance |
| rs4486393 | 1:24,463,563 | T/C | — | benign |
| rs1475503449 | 1:24,463,710 | G/A | — | uncertain significance |
| rs758989459 | 1:24,463,734 | A/T | — | uncertain significance |
| rs376646024 | 1:24,463,743 | G/A | — | uncertain significance |
| rs770672223 | 1:24,463,753 | T/C | — | uncertain significance |
| rs200680853 | 1:24,463,758 | C/T | — | uncertain significance |
| rs556183942 | 1:24,463,769 | C/G | — | uncertain significance |
| rs761583215 | 1:24,463,795 | C/T | — | uncertain significance |
| rs41268137 | 1:24,463,854 | T/C | — | benign |
| rs10903022 | 1:24,465,113 | C/T | — | benign |
| rs199753143 | 1:24,465,118 | C/T | — | uncertain significance |
| rs141565535 | 1:24,465,199 | C/G | — | uncertain significance |
| rs10794642 | 1:24,465,309 | C/T | — | benign |
| rs12047417 | 1:24,467,256 | G/A | intron variant | — |
| rs142059608 | 1:24,469,455 | G/A | regulatory region variant | — |
| rs370338743 | 1:24,469,538 | G/A | — | uncertain significance |
| rs10794644 | 1:24,470,902 | G/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.