Trait
SNPs associated with C-reactive protein measurement
2084 genetic variants across 309 genes have been associated with C-reactive protein measurement in published research. Key genes include ABCA6, ABCB11, ABCG2.
Associated variants2,084 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2794520 | CRP | GWAS association (p=2.0e-186) | Meta-analysis |
| rs1260326 | GCKR | GWAS association (p=5.0e-40) | Meta-analysis |
| rs4129267 | IL6R | GWAS association (p=2.0e-48) | Meta-analysis |
| rs1183910 | HNF1A | GWAS association (p=2.0e-124) | Meta-analysis |
| rs6734238 | — | GWAS association (p=2.0e-17) | Meta-analysis |
| rs12239046 | NLRP3 | GWAS association (p=1.0e-15) | Meta-analysis |
| rs1800961 | HNF4A | GWAS association (p=2.0e-09) | Meta-analysis |
| rs10521222 | — | GWAS association (p=9.0e-13) | Meta-analysis |
| rs4420065 | — | GWAS association (p=4.0e-62) | Meta-analysis |
| rs4420638 | APOC1 | GWAS association (p=9.0e-139) | Meta-analysis |
| rs13233571 | BCL7B | GWAS association (p=4.0e-09) | Meta-analysis |
| rs9987289 | LOC157273 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs10745954 | C12orf42 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs12037222 | — | GWAS association (p=6.0e-11) | Meta-analysis |
| rs340029 | RORA | GWAS association (p=4.0e-09) | Meta-analysis |
| rs4705952 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs2847281 | PTPN2 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs6901250 | GPRC6A | GWAS association (p=5.0e-08) | Meta-analysis |
| rs769449 | APOE | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs11265260 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs2244608 | HNF1A | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs142042446 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs34095326 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs483082 | APOC1 | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs584007 | — | GWAS association (p=4.0e-290) | Major Consortium Study |
| rs77832441 | CRP | GWAS association (p=4.0e-287) | Major Consortium Study |
| rs4131568 | — | GWAS association (p=2.0e-284) | Major Consortium Study |
| rs4394621 | — | GWAS association (p=9.0e-276) | Major Consortium Study |
| rs17616063 | — | GWAS association (p=7.0e-248) | Major Consortium Study |
| rs7305618 | — | GWAS association (p=3.0e-217) | Major Consortium Study |
| rs1800947 | CRP | GWAS association (p=2.0e-200) | Major Consortium Study |
| rs41289512 | — | GWAS association (p=1.0e-198) | Major Consortium Study |
| rs780094 | GCKR | GWAS association (p=2.0e-196) | Major Consortium Study |
| rs76366838 | — | GWAS association (p=2.0e-191) | Major Consortium Study |
| rs60049679 | — | GWAS association (p=4.0e-169) | Major Consortium Study |
| rs11668327 | — | GWAS association (p=1.0e-155) | Major Consortium Study |
| rs12691088 | — | GWAS association (p=8.0e-145) | Major Consortium Study |
| rs116971887 | — | GWAS association (p=2.0e-121) | Major Consortium Study |
| rs7553007 | — | GWAS association (p=2.0e-116) | Major Consortium Study |
| rs28399637 | — | GWAS association (p=4.0e-116) | Major Consortium Study |
| rs6859 | NECTIN2 | GWAS association (p=6.0e-115) | Major Consortium Study |
| rs117310449 | — | GWAS association (p=4.0e-112) | Major Consortium Study |
| rs144261139 | — | GWAS association (p=1.0e-109) | Major Consortium Study |
| rs405697 | — | GWAS association (p=1.0e-107) | Major Consortium Study |
| rs7412 | APOE | GWAS association (p=5.0e-105) | Major Consortium Study |
| rs1386821 | — | GWAS association (p=4.0e-97) | Major Consortium Study |
| rs72698573 | — | GWAS association (p=4.0e-97) | Major Consortium Study |
| rs17459069 | — | GWAS association (p=1.0e-89) | Major Consortium Study |
| rs72683129 | — | GWAS association (p=2.0e-89) | Major Consortium Study |
| rs12819210 | — | GWAS association (p=5.0e-84) | Major Consortium Study |
| rs769450 | APOE | GWAS association (p=4.0e-76) | Major Consortium Study |
| rs6672331 | — | GWAS association (p=5.0e-76) | Major Consortium Study |
| rs59330569 | — | GWAS association (p=6.0e-74) | Major Consortium Study |
| rs17457976 | — | GWAS association (p=2.0e-69) | Major Consortium Study |
| rs115381557 | — | GWAS association (p=2.0e-66) | Major Consortium Study |
| rs10494326 | — | GWAS association (p=2.0e-65) | Major Consortium Study |
| rs365653 | — | GWAS association (p=6.0e-62) | Major Consortium Study |
| rs983309 | — | GWAS association (p=5.0e-61) | Major Consortium Study |
| rs141622900 | — | GWAS association (p=9.0e-61) | Major Consortium Study |
| rs12044132 | — | GWAS association (p=9.0e-59) | Major Consortium Study |
| rs6698040 | — | GWAS association (p=9.0e-58) | Major Consortium Study |
| rs2111125 | — | GWAS association (p=1.0e-55) | Major Consortium Study |
| rs80051818 | EIF2B4 | GWAS association (p=5.0e-55) | Major Consortium Study |
| rs17434647 | — | GWAS association (p=1.0e-53) | Major Consortium Study |
| rs12745083 | — | GWAS association (p=1.0e-50) | Major Consortium Study |
| rs77994623 | — | GWAS association (p=3.0e-50) | Major Consortium Study |
| rs11665829 | NECTIN2 | GWAS association (p=6.0e-50) | Major Consortium Study |
| rs3027067 | — | GWAS association (p=2.0e-49) | Major Consortium Study |
| rs3745150 | — | GWAS association (p=3.0e-49) | Major Consortium Study |
| rs28929474 | SERPINA1 | GWAS association (p=3.0e-49) | Major Consortium Study |
| rs11065387 | — | GWAS association (p=6.0e-49) | Major Consortium Study |
| rs76912411 | — | GWAS association (p=2.0e-48) | Major Consortium Study |
| rs7302482 | — | GWAS association (p=2.0e-48) | Major Consortium Study |
| rs1169284 | — | GWAS association (p=4.0e-48) | Major Consortium Study |
| rs1169282 | — | GWAS association (p=3.0e-47) | Major Consortium Study |
| rs370370301 | CRP | GWAS association (p=1.0e-46) | Major Consortium Study |
| rs115585839 | — | GWAS association (p=1.0e-45) | Major Consortium Study |
| rs12042349 | — | GWAS association (p=1.0e-44) | Major Consortium Study |
| rs117264457 | — | GWAS association (p=2.0e-44) | Major Consortium Study |
| rs72685056 | — | GWAS association (p=3.0e-44) | Major Consortium Study |
| rs71454665 | — | GWAS association (p=5.0e-44) | Major Consortium Study |
| rs416041 | — | GWAS association (p=8.0e-44) | Major Consortium Study |
| rs61811421 | — | GWAS association (p=1.0e-43) | Major Consortium Study |
| rs10849772 | — | GWAS association (p=1.0e-43) | Major Consortium Study |
| rs6728590 | — | GWAS association (p=2.0e-43) | Major Consortium Study |
| rs12816397 | — | GWAS association (p=2.0e-43) | Major Consortium Study |
| rs118106133 | — | GWAS association (p=1.0e-42) | Major Consortium Study |
| rs138607350 | NECTIN2 | GWAS association (p=8.0e-42) | Major Consortium Study |
| rs1160984 | — | GWAS association (p=5.0e-41) | Major Consortium Study |
| rs7254892 | — | GWAS association (p=2.0e-40) | Major Consortium Study |
| rs2245407 | — | GWAS association (p=4.0e-40) | Major Consortium Study |
| rs862994 | — | GWAS association (p=2.0e-39) | Major Consortium Study |
| rs113188187 | — | GWAS association (p=3.0e-39) | Major Consortium Study |
| rs114530473 | — | GWAS association (p=2.0e-38) | Major Consortium Study |
| rs3093070 | — | GWAS association (p=1.0e-37) | Major Consortium Study |
| rs12610605 | — | GWAS association (p=8.0e-37) | Major Consortium Study |
| rs2965164 | — | GWAS association (p=9.0e-36) | Major Consortium Study |
| rs72654472 | — | GWAS association (p=1.0e-34) | Major Consortium Study |
| rs72698555 | — | GWAS association (p=2.0e-34) | Major Consortium Study |
Showing the top 100 of 2,084 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.