rs1160984

GWAS Catalog Trait Associations (11)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-reactive protein measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.07
p 5.0e-41
N 355,127
Major Consortium StudyLarge GWAS
multi-ancestry

Alzheimer disease

Allele T
OR 0.05
p 1.0e-20
N 640,258
Large GWAS
European

Alzheimer disease, family history of Alzheimer’s disease

Allele T
OR 9.29
p 2.0e-20
N 455,258
Meta-analysisLarge GWAS
European

total cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.05
p 4.0e-20
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry

alkaline phosphatase measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.05
p 4.0e-18
N 355,891
Major Consortium StudyLarge GWAS
multi-ancestry

low density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.05
p 2.0e-17
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry

apolipoprotein B measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.04
p 1.0e-16
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry

fatty acid amount

Allele T
OR
p 2.0e-15
N 239,268
Large GWAS
European

triglyceride measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.04
p 5.0e-14
N 355,577
Major Consortium StudyLarge GWAS
multi-ancestry
Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele T
OR 0.04
p 4.0e-12
N 361,194
Large GWAS
European

Alzheimer's disease biomarker measurement

Allele T
OR 0.03
p 3.0e-12
N 568,836
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…