IRGC
immunity related GTPase cinema
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in positive regulation of flagellated sperm motility. Located in lipid droplet and sperm mitochondrial sheath. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants38 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs141156174 | 19:44,218,887 | G/A | upstream gene variant | — |
| rs1429007586 | 19:44,222,729 | C/T | — | uncertain significance |
| rs754906907 | 19:44,222,732 | G/A | — | uncertain significance |
| rs2513872902 | 19:44,222,759 | A/G | — | uncertain significance |
| rs755942419 | 19:44,222,889 | C/T | — | uncertain significance |
| rs139023590 | 19:44,222,897 | T/C | — | uncertain significance |
| rs1968215496 | 19:44,222,958 | G/C | — | uncertain significance |
| rs372481323 | 19:44,223,029 | G/T | — | uncertain significance |
| rs139284118 | 19:44,223,067 | C/T | — | likely benign |
| rs139419159 | 19:44,223,086 | C/G | — | uncertain significance |
| rs1568586153 | 19:44,223,107 | C/T | — | uncertain significance |
| rs780321714 | 19:44,223,131 | T/G | — | uncertain significance |
| rs773895502 | 19:44,223,137 | C/T | — | uncertain significance |
| rs764477711 | 19:44,223,141 | G/A | — | uncertain significance |
| rs370201430 | 19:44,223,152 | G/A | — | uncertain significance |
| rs569979617 | 19:44,223,162 | G/A | — | uncertain significance |
| rs1968224771 | 19:44,223,252 | G/A | — | uncertain significance |
| rs145052313 | 19:44,223,271 | G/A | — | benign |
| rs866180953 | 19:44,223,305 | G/A | — | uncertain significance |
| rs1968227249 | 19:44,223,339 | C/G | — | uncertain significance |
| rs2146337078 | 19:44,223,479 | C/G | — | uncertain significance |
| rs762085853 | 19:44,223,572 | G/A | — | uncertain significance |
| rs201085444 | 19:44,223,621 | G/T | — | uncertain significance |
| rs34051422 | 19:44,223,667 | G/C | — | benign |
| rs138990135 | 19:44,223,681 | G/A | — | uncertain significance |
| rs34432569 | 19:44,223,694 | G/A | — | likely benign |
| rs369246997 | 19:44,223,719 | G/A | — | uncertain significance |
| rs199882680 | 19:44,223,759 | C/T | — | uncertain significance |
| rs1232907153 | 19:44,223,824 | G/C | — | uncertain significance |
| rs140840883 | 19:44,223,833 | G/A | — | uncertain significance |
| rs528054051 | 19:44,223,848 | G/A | — | likely benign |
| rs762313797 | 19:44,223,986 | G/C | — | likely benign |
| rs200254217 | 19:44,223,990 | G/A | — | uncertain significance |
| rs76105613 | 19:44,223,995 | G/A | — | uncertain significance |
| rs1968246211 | 19:44,224,008 | G/A | — | uncertain significance |
| rs755229281 | 19:44,224,075 | G/C | — | uncertain significance |
| rs2513877679 | 19:44,224,078 | G/C | — | uncertain significance |
| rs965718503 | 19:44,224,089 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.