rs141156174

This is a upstream gene variant variant in the IRGC gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cD177 antigen measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.27

p 3.0e-13

N 47,745

Large GWAS

European

About IRGC

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in positive regulation of flagellated sperm motility. Located in lipid droplet and sperm mitochondrial sheath. [provided by Alliance of Genome Resources, Jul 2025]

View all IRGC variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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