KIF21B

kinesin family member 21B

Summary

This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Known Variants143 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs757337335	1:200,943,242	C/T	—	uncertain significance
rs2465110937	1:200,943,252	T/C	—	uncertain significance
rs1252446264	1:200,943,959	G/A	—	uncertain significance
rs367842661	1:200,943,992	G/A	—	uncertain significance
rs893498810	1:200,944,031	T/C	—	conflicting classifications of pathogenicity
rs200282109	1:200,944,044	G/C	—	uncertain significance
rs296565	1:200,944,057	G/A	—	benign
rs769986420	1:200,944,677	G/A	—	uncertain significance
rs372866126	1:200,944,703	T/A	—	uncertain significance
rs267598287	1:200,944,720	G/C	—	uncertain significance
rs1477823118	1:200,944,782	C/T	—	uncertain significance
rs142799216	1:200,945,936	C/T	—	uncertain significance
rs371235023	1:200,945,968	G/A	—	uncertain significance
rs759837389	1:200,946,362	C/T	—	uncertain significance
rs375949029	1:200,946,380	C/T	—	uncertain significance
rs1041368136	1:200,946,434	C/T	—	uncertain significance
rs1217111451	1:200,948,694	G/A	—	uncertain significance
rs1571912705	1:200,948,713	G/A	—	likely benign
rs74962326	1:200,948,780	G/A	—	likely benign
rs2465132244	1:200,948,825	C/T	—	uncertain significance
rs1247555499	1:200,948,829	T/A	—	uncertain significance
rs145377208	1:200,950,144	G/T	—	uncertain significance
rs1655878067	1:200,950,181	C/T	—	uncertain significance
rs751902877	1:200,950,195	T/C	—	uncertain significance
rs2465148020	1:200,954,071	G/T	—	uncertain significance
rs139250432	1:200,955,992	G/A	—	likely benign
rs369653840	1:200,956,020	G/A	—	uncertain significance
rs74138804	1:200,956,050	C/A	—	benign
rs1459053056	1:200,956,131	T/A	—	uncertain significance
rs796052152	1:200,956,137	G/A	—	uncertain significance
rs375407145	1:200,956,157	C/T	—	uncertain significance
rs376964063	1:200,956,173	G/C	—	uncertain significance
rs2465154746	1:200,956,181	G/A	—	uncertain significance
rs371053876	1:200,956,187	C/T	—	uncertain significance
rs367975021	1:200,956,291	C/T	—	likely benign
rs1185314463	1:200,956,296	C/G	—	uncertain significance
rs765567729	1:200,957,622	T/G	—	uncertain significance
rs759165397	1:200,957,933	G/A	—	uncertain significance
rs764300358	1:200,957,951	G/A	—	uncertain significance
rs746818505	1:200,958,008	G/C	—	uncertain significance
rs2465164774	1:200,959,123	G/T	—	uncertain significance
rs1416098796	1:200,959,149	G/T	—	uncertain significance
rs748591412	1:200,959,169	C/T	—	likely benign
rs983020699	1:200,959,286	C/T	—	uncertain significance
rs2297911	1:200,959,302	G/A	—	benign
rs1656589224	1:200,959,304	C/T	—	uncertain significance
rs763592461	1:200,959,415	G/A	—	uncertain significance
rs61740468	1:200,959,728	C/T	—	benign
rs373553632	1:200,959,735	T/C	—	uncertain significance
rs779775292	1:200,959,774	C/T	—	uncertain significance
rs1212624082	1:200,960,055	G/A	—	uncertain significance
rs2465168934	1:200,960,069	G/A	—	uncertain significance
rs763113039	1:200,960,073	G/A	—	uncertain significance
rs1479866453	1:200,960,136	C/A	—	uncertain significance
rs142914751	1:200,960,142	G/A	—	uncertain significance
rs750541983	1:200,960,174	C/T	—	uncertain significance
rs141958232	1:200,960,204	A/G	—	uncertain significance
rs138915096	1:200,960,207	G/C	—	uncertain significance
rs141871941	1:200,960,225	C/T	—	likely benign
rs765068592	1:200,960,261	C/T	—	uncertain significance
rs2297909	1:200,960,307	G/T	—	—
rs2465171820	1:200,960,831	G/A	—	uncertain significance
rs776829182	1:200,960,843	C/T	—	uncertain significance
rs1266346444	1:200,961,450	C/T	—	uncertain significance
rs771950376	1:200,961,451	G/A	—	uncertain significance
rs2102415502	1:200,961,460	T/C	—	uncertain significance
rs750865418	1:200,965,377	C/T	—	uncertain significance
rs80251189	1:200,965,378	G/A	—	likely benign
rs753937959	1:200,965,382	C/T	—	uncertain significance
rs1240133411	1:200,965,385	G/A	—	uncertain significance
rs2465186850	1:200,965,389	G/C	—	uncertain significance
rs2465187204	1:200,965,442	T/C	—	uncertain significance
rs1345199231	1:200,965,445	C/T	—	uncertain significance
rs149084633	1:200,965,456	C/T	—	likely benign
rs529917183	1:200,965,457	C/T	—	uncertain significance
rs1657070675	1:200,965,522	G/T	—	uncertain significance
rs2102431074	1:200,967,602	G/A	—	uncertain significance
rs61740473	1:200,967,687	C/G	—	benign
rs201900169	1:200,968,526	C/G	—	likely benign
rs779310643	1:200,968,527	G/A	—	uncertain significance
rs778202622	1:200,968,542	T/A	—	uncertain significance
rs200764096	1:200,968,546	C/T	—	benign
rs147761216	1:200,968,548	C/T	—	conflicting classifications of pathogenicity
rs373134245	1:200,968,581	C/G	—	uncertain significance
rs760922988	1:200,969,088	C/T	—	uncertain significance
rs762774383	1:200,969,528	G/A	—	uncertain significance
rs140654082	1:200,969,544	C/T	—	benign
rs2102438018	1:200,969,615	G/A	—	uncertain significance
rs1175085100	1:200,969,707	T/C	—	uncertain significance
rs145642006	1:200,969,713	G/A	—	uncertain significance
rs16847518	1:200,969,743	A/G	—	benign
rs2465208525	1:200,969,867	T/A	—	uncertain significance
rs1173110225	1:200,971,297	G/T	—	uncertain significance
rs1408476064	1:200,971,319	G/C	—	uncertain significance
rs769663553	1:200,971,325	T/C	—	uncertain significance
rs2465215193	1:200,971,352	C/G	—	uncertain significance
rs1476058834	1:200,971,375	T/G	—	uncertain significance
rs937853917	1:200,971,382	G/A	—	uncertain significance
rs140412174	1:200,971,427	G/A	—	uncertain significance
rs2102443880	1:200,971,478	C/T	—	uncertain significance

Showing 100 of 143 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.