Trait
SNPs associated with Ankylosing Spondylitis
64 genetic variants across 28 genes have been associated with Ankylosing Spondylitis in published research. Key genes include ANO6, C10orf90, C11orf40.
Associated variants64 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs11209026 | IL23R | Protective against ankylosing spondylitis risk | Meta-analysis |
| rs17190120 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs896425173 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs141561509 | DOCK4 | GWAS association (p=8.0e-14) | Major Consortium Study |
| rs530496300 | — | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs189622470 | TENM4 | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs28826344 | LINC02141 | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs13001372 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs529860248 | LINC01036 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs188905330 | LOC124901815 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs191941550 | PDE8A | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs181590288 | LMO4 | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs564715039 | — | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs540778631 | C10orf90 | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs544460457 | LOC105377759 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs576451181 | KIF18A | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs142569411 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs552646385 | LOC105376600 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs141048732 | MIR4527HG | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs573279630 | C11orf40 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs544909513 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs183205659 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs571222194 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs368276108 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs563260345 | LOC105372747 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs567303840 | — | GWAS association (p=5.0e-11) | Major Consortium Study |
| rs4349859 | HLA-B | Higher ankylosing spondylitis risk | Large GWAS |
| rs10865331 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs2910686 | ERAP1 | GWAS association (p=5.0e-17) | Large GWAS |
| rs41299637 | INAVA | GWAS association (p=7.0e-16) | Large GWAS |
| rs4129267 | IL6R | GWAS association (p=2.0e-15) | Large GWAS |
| rs11190133 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs10045403 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs148783236 | USP8 | GWAS association (p=1.0e-13) | Large GWAS |
| rs61752717 | MEFV | GWAS association (p=2.0e-12) | Large GWAS |
| rs11616188 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs27434 | ERAP1 | GWAS association (p=5.0e-12) | Large GWAS |
| rs2297909 | KIF21B | GWAS association (p=5.0e-12) | Large GWAS |
| rs378108 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs11249215 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs12141575 | — | GWAS association (p=9.0e-11) | Large GWAS |
| rs2531875 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs11624293 | LINC01147 | GWAS association (p=2.0e-10) | Large GWAS |
| rs35164067 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs4552569 | — | GWAS association (p=9.0e-10) | Large GWAS |
| rs12615545 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs1801274 | FCGR2A | GWAS association (p=1.0e-09) | Large GWAS |
| rs27529 | ERAP1 | GWAS association (p=1.0e-09) | Large GWAS |
| rs1128905 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs1250550 | ZMIZ1 | GWAS association (p=2.0e-09) | Large GWAS |
| rs7282490 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs4676410 | GPR35 | GWAS association (p=1.0e-08) | Large GWAS |
| rs17095830 | ANO6 | GWAS association (p=2.0e-08) | Large GWAS |
| rs6556416 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs17765610 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs6871626 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs8070463 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs11065898 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs30187 | ERAP1 | GWAS association (p=4.0e-45) | Large GWAS |
| rs6600247 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs6759298 | — | GWAS association (p=5.0e-47) | Large GWAS |
| rs1860545 | TNFRSF1A | GWAS association (p=3.0e-10) | Large GWAS |
| rs9901869 | — | GWAS association (p=6.0e-15) | Large GWAS |
| rs2836883 | — | GWAS association (p=7.0e-17) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.