INAVA
innate immunity activator
Summary
Involved in several processes, including nucleotide-binding activity oligomerization domain containing 2 signaling pathway; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in cytoplasm and nuclear body. Implicated in inflammatory bowel disease 29. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants18 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs141245080 | 1:200,860,731 | G/C | — | benign |
| rs41269923 | 1:200,867,572 | T/A | — | benign |
| rs773330158 | 1:200,868,723 | G/T | — | uncertain significance |
| rs150962388 | 1:200,869,239 | C/T | — | likely benign |
| rs34596202 | 1:200,869,306 | C/T | — | benign |
| rs55838263 | 1:200,874,728 | A/G | regulatory region variant | — |
| rs12132298 | 1:200,875,095 | T/C | regulatory region variant | — |
| rs59655222 | 1:200,875,897 | T/C | intron variant | — |
| rs7554511 | 1:200,877,562 | C/A | intron variant | — |
| rs41299637 | 1:200,877,850 | T/G | splice region variant | — |
| rs1571870529 | 1:200,878,018 | C/A | — | uncertain significance |
| rs41313912 | 1:200,878,026 | A/T | — | conflicting classifications of pathogenicity |
| rs777677539 | 1:200,880,701 | G/A | — | likely benign |
| rs116087951 | 1:200,880,817 | C/G | — | likely benign |
| rs772463898 | 1:200,880,879 | G/A | — | uncertain significance |
| rs296520 | 1:200,880,978 | C/T | — | benign |
| rs61745433 | 1:200,881,026 | C/T | — | benign |
| rs7522462 | 1:200,881,595 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.