rs12132298
This is a regulatory region variant variant in the INAVA gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bipolar disorder, inflammatory bowel disease
Wang BR et al. “Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.” Journal of Affective Disorders 348:167-174 (2024)
Allele T
OR 0.01
p 8.0e-9
N 473,423
Large GWAS
European
About INAVA
Involved in several processes, including nucleotide-binding activity oligomerization domain containing 2 signaling pathway; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in cytoplasm and nuclear body. Implicated in inflammatory bowel disease 29. [provided by Alliance of Genome Resources, Jul 2025]
View all INAVA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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